Discover and read the best of Twitter Threads about #fusiononcoproteins
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Congrats to Hayley Zullow of @kadochlab @HarvardMITmdphd @BBS_Harvard programs and our team, including @akshaysci, @JunQiLab, @ar_davino, and many others, on this exciting new study out today in @MolecularCell @CellPressNews ! Tweetorial below: (1/7) cell.com/molecular-cell…
Here, we explore the impact of the #fusion oncoprotein hallmark to #myxoidliposarcoma, FUS-DDIT3, and its impact on #BAF #SWISNF complex-mediated #chromatin remodeling activities genome wide. (2/7)
We previously showed that fusions such as SS18-SSX and EWS-FLI1, in #synovialsarcoma and #Ewingsarcoma, respectively, interact with BAF complexes and direct their genomic occupancy in a cancer-specific, gain-of-function manner. (3/7)
