Discover and read the best of Twitter Threads about #gca

Most recents (3)

¿Cómo debemos sospechar #aortitis y cuándo sospecharla?
Dr. Javier Loricera García
#25TenTopicsBCN #TenTopics
¿Cómo debemos sospechar #aortitis y cuándo sospecharla? Etiologías
#25TenTopicsBCN #TenTopics
¿Cómo debemos sospechar #aortitis y cuándo sospecharla? #Aortitis #infecciosa
#25TenTopicsBCN #TenTopics
Read 14 tweets
My summary of Prof Cornelia Weyand’s lecture on #GCA pathogenesis at @Vasculitis2022 (follow their account to see the slides themselves, but here’s what I took away)

#vasculitis22

Thread 1/7 🧵
2/7
Four phases of #GCA pathogenesis with “checkpoints” between each
•Genetic risk, environmental exposure
•Loss of self tolerance
•Loss of tissue tolerance
•Arteritis

#vasculitis22
3/7
Genetic risk for #GCA: HLA; other
Environmental exposures

The subsequent three stages have all been studied in the “avatar” model of immunodeficiency mouse + temporal artery + human immune cells

#Vasculitis22
Read 7 tweets

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