Discover and read the best of Twitter Threads about #genes

Most recents (24)

Sehr aktueller Preprint zu #longcovid und #Genalayse und #GProteinGekoppelteRezeptoren

Kurze Zusammenfassung / Short summary of this data analysis

Long COVID: G Protein-Coupled Receptors (GPCRs) responsible for persistent post-COVID symptoms biorxiv.org/content/10.110…
Durch computergestützte Methoden wurden 255 #LongCOVID-#Symptome analysiert und die dazu relevanten Gene identifiziert.

This work utilised computational methods to analyse the persistence of COVID symptoms after recovery and to identify the relevant genes.
Protein-protein interaction network overview. Nodes = proteins, edges represent the interaction between two nodes (proteins). The top 10 key hub #genes of 255 symptoms of #longcovid are related to G-protein coupled receptors shown in circular nodes in pink.
Read 11 tweets
🧵#Bioinformatics and its impact on #healthcare, a THREAD🧵🧵:
#Bioinformatics is the application of #computational techniques to the analysis of #biological data, such as #DNA sequences and #protein #structures.
In #healthcare, #bioinformatics is used to gain insights into the #genetic basis of diseases, and to develop new #diagnostic tests and #treatments.
Read 11 tweets
Are you interested in learning about #bioinformatics and working with #genomic data? Here's a detailed #learning path to get you started:
To build a strong foundation in biology, you'll need to learn about:
The #structure and #function of #cells, including the various #organelles and their roles in the cell. This will help you understand how cells work and how they carry out essential functions such as #metabolism and #energy production.
Read 12 tweets
🧵#Bioinformatics applied to genomics, a THREAD🧵🧵:
#Genomics is the study of the entire #genetic makeup of an #organism, including its #DNA sequence, #gene structure, and regulation of #gene #expression.
#Bioinformatics is the application of computational techniques, such as #machine #learning and data mining, to the analysis of large datasets of biological information, such as #genomic, #proteomic, and #metabolomic data.
Read 9 tweets
🦠GENES HUMANOS asociados a severidad de #COVID

ABRO 🧵 EXPLICANDO:
➡️¿Por qué son importantes?
➡️¿Qué podemos hacer con ellos?
➡️Te presentó a algunos de los genes asociados a #COVIDGrave

ABRO 🧵
1)🧬 INTRODUCCIÓN
#GenesHumanos #COVID

➡️Todos tenemos estos genes
➡️Existen variaciones del gen, que algunas personas tienen
➡️Tratamos de identificar que variaciones son las que aumentan el riesgo
➡️Puede ser que una variación aumente/disminuya/inhiba la función del gen
2) IMPORTANCIA
🚨 Al identificarlos estamos un paso mas cerca de
➡️Identificar personas con más riesgo
➡️Encontrar nuevos diagnósticos y tratamientos
➡️Medicina personalizada
Read 11 tweets
Me pidieron hilos sobre inmuno básica así que va lo básico de lo básico...

¿DE DÓNDE SALIÓ EL SISTEMA INMUNITARIO HUMANO? 🧐

Nuestro sistema de defensa es exquisitamente complejo, esta complejidad se desarrolló a lo largo de millones de años y continúa evolucionando

🧵👇🏼

1/19
Aclaración inicial: el ser humano moderno tiene por mucho 300mil años de existencia¹ (referencias al final del 🧵), menciono millones de años de evolución porque el sistema inmunitario no apareció con nosotros, sino con nuestros ancestros 🌍

2/19

#Evolution #ImmuneSystem
De hecho, la inmunidad adaptativa surgió hace aprox 400 millones de años con los placodermos²

En fin…definamos de manera general 2 conceptos: evolución y genes

La evolución biológica se refiere al cambio constante q presentan las distintas especies a lo largo del tiempo

3/19
Read 20 tweets
While #science thought us that we can even cut and paste #genes with #CRISPR technology…even with that we only influence 3% to 5% of #chronicillness. The rest depends on #how you #live your #life!!! So how do we #SelfRegulate our #body?
1. Good #sleep is more important than most think! What happens during sleep? The fluctuation of consciousness…that we call the waking state. But in many wisdom traditions of the world, the waking state is merely a lucid dream that consciousness is having…
Read 41 tweets
Some people do bad things, but, they don't look bad.
They are others who do good, but, they don't look good.
It's how we are intrinsically made, that shapes our personality, defines our intentions and describes our actions.
Our #DNA is the repository that informs our evolution.
Ask the maker why he made it?
Not from the doer.
We human beings are at the receiving end, always!!
We are what we are!
We all are made according to a certain specification list.
If we try to mutate ourselves forcefully too much, we won't remain what we are.
Be #Adaptative without violating the complex laws of nature.
Read 6 tweets
1/ Did you know that you can use your genetic raw data file from #23andMe or #AncestryDNA to learn more about your health?

A thread on using your data to optimize health and prevent chronic disease 🧵
2/ When getting started learning about how your #genes impact susceptibility to chronic disease, it can be overwhelming.

It isn't like high school science when you learned you inherited the 'brown eye gene' or the 'short gene'.
3/ Most chronic diseases, like #diabetes or #heart disease, have a genetic component. But it is a combination of multiple genetic variants along with lifestyle factors that lead to disease.
Read 5 tweets
#Espace - Les bonnes raisons d'y aller
🌿À l'heure de la #COP26, pourquoi dépenser de l'énergie et des finances pour aller dans l'espace. #Thread de quelques éléments de réponses du côté optimiste de la force 🤞
#espace #écologie #spacegeek Space final frontier - illustration Elite Dangerous
1. Pour trouver notre place dans l'#univers, #explorer, #rêver.
Historiquement, l'observation des étoiles a interrogé, fait rêver. Domaine des dieux, sphère céleste, on étudie le ciel nocturne et l'évolution de soleil en journée qui rythme les vies.
#astronomie #histoire #Science
🔭Les #philosophes déblayant les principes de la mécanique céleste posent les bases de l'#astronomie moderne, s'égarant parfois dans des interprétations erronées. Les briques sont posées et ainsi naîtra les #science, #physique, #astrologie, ...
Read 29 tweets
"The promise & peril of the Bio Revolution"

"...the world cheered [] that 3 #gene-based COVID19 #vaccines – 1 developed by German #biotech co. BioNTech in collab. w/ Pfizer, another by [] biotech firm Moderna, & a 3rd by [] AstraZeneca – had proved effective in clinical trials."
"But in October, researchers revealed that off-target effects of the #CRISPR-Cas9 #gene-editing tool used to repair a blindness-causing gene in the early stages of human #embryo development often eliminated an entire #chromosome or a large part of it."

#BioengineeringEconomy
"Our deepening knowledge of #biology#genes, #microbiomes, & neural signals – is making it increasingly possible to "engineer life."... #gene drives applied to infectious-disease vectors [] could save many lives, but we may not be able to control them."

#4IR #Biotech
Read 9 tweets
On #InternationalWomensDay we'd like to pause and celebrate just a small slice of the enormous contributions to science women have made here at SFI.

Read the thread below for links to some of their own favorite research papers, and a few nominated by other SFI faculty members:
First off, these papers on #FoodWebs led by our VP for #Science, Jennifer Dunne:

[@royalsociety Proceedings B]
royalsocietypublishing.org/doi/10.1098/rs…

[@PLOSBiology]
doi.org/10.1371/journa…

...and this interview she did for @QuantaMagazine:
quantamagazine.org/with-food-webs…

#Ecology #Ecologist
Next, two papers on how humans navigate and process #information co-authored by SFI External Prof @DaniSBassett (@Penn):

[@NatureHumBehav]
nature.com/articles/s4156…
+ summary:
blog.seas.upenn.edu/studying-hunte…

[@nature]
nature.com/articles/s4156…
+ summary:
penntoday.upenn.edu/news/what-do-b…
Read 21 tweets
Daily Bookmarks to GAVNet 12/02/2020 greeneracresvaluenetwork.wordpress.com/2020/12/02/dai…
Preserving a Sense of Wonder in DNA - Issue 92: Frontiers - Nautilus

nautil.us/issue/92/front…

#dna
The ocean in humanity’s future

nature.com/immersive/d428…

#future #humanity #ocean
Read 8 tweets
Check out our new paper by @smartinezarbas et al. about #CRISPR mediated interactions within a wastewater #microbiome in @NatureMicrobiol! Exciting collaboration between @uni_lu @TGen @IUBloomington @isbsci @KU_Leuven. Funding by @FnrLux
nature.com/articles/s4156…

A 🧵👇

1/9
In parallel with recent work of @mhe345 @NatureComms nature.com/articles/s4146…, we explored the roles of #plasmids and #phages within a wastewater treatment plant microbial community, using longitudinal integrated #omics data 2/9
We identified 31 bacterial MAGs with complete #CRISPR-Cas systems from the 14-months data set. These MAGs served as the basis for downstream population-level analyses of #CRISPR interactions 3/9
Read 9 tweets
The Aristocracy - Survival of the Fittest via @YouTube
Actually, this documentary has set my mind into commotion and took me back into those years when the New #Labour and #Blair came into power in the late 1990s in the #UK.
We eagerly watched what reforms under the #collectivists would imply, as the UK had a manifest #class system.
The worse thing which #Blair could do, at that time, was to remove the #hereditary #peers from the House of #Lords.
This particular political decision had far-reaching consequences for the #British Society,as a vernacular mindset that rejected #evolution & tradition jointly arose
Read 12 tweets
What your are thinking right now is having an impact on your genetic expression and in turn your health. What you are feeling right now is having an impact on your genetic expression and in turn your health.
What emotion you are going through right now is having and impact on your genetic expression and in turn your health.
Your thoughts, feelings and emotions impact your biology! If your emotions can bring such a physical and mental change in you, you now know how it’s impacting your genes at a cellular level too! When they say genetic most people give up like there is nothing to do.
Read 7 tweets
Daily Bookmarks to GAVNet 09/03/2020 greeneracresvaluenetwork.wordpress.com/2020/09/03/dai…
Opinion | It Has Come to This: Ignore the C.D.C. - The New York Times

nytimes.com/2020/08/31/opi…

#coronavirus #CDC #COVID19
By Losing Genes, Life Often Evolved More Complexity | Quanta Magazine

quantamagazine.org/by-losing-gene…

#complexity #life #genes
Read 7 tweets
(1/13) Please RT: our first #tweetorial!

Here's a 🧵on our new paper which is also my 1st time being (joint) last author✍️

Congrats to all, especially superstar med student @LuszczakSabina!

#AcademicTwitter @AcademicChatter @OpenAcademics #womeninSTEM

nature.com/articles/s4159…
(2/13) In #prostatecancer cell lines & human tissue, co-targeting #PIM & #PI3K #kinases seems promising!

We reckon ~20% of prostate cancer patients could benefit from this approach in future & these tend to be the sicker patients.

Scroll for #science!

nature.com/articles/s4159…
(3/13) Fig1a:

From publicly available data we see that some patients overexpress either the #PIM pathway, the #PI3K pathway, or both. Each of these targets have inhibitors in development, that could theoretically be of benefit to any of these patient groups when combined 🤞
Read 13 tweets
Daily Bookmarks to GAVNet 08/01/2020 greeneracresvaluenetwork.wordpress.com/2020/08/01/dai…
Election Integrity and Technology: Vulnerabilities and Solutions

georgetownlawtechreview.org/election-integ…

#election #integrity #technology
Expanded ENCODE delivers invaluable genomic encyclopedia

nature.com/articles/d4158…

#protein #genes #encode
Read 6 tweets
📢🎉The work of #Bat1K is featured on the cover in the latest issue of @nature: “Six reference-quality #genomes reveal evolution of #bat adaptations” 🦇🧬 #bats Our thread 👇 on the paper:nature.com/articles/s4158… 📸: Olivier Farcy(1/n) Image
📢Have you ever wondered how 🦇 manage to do what they do? #bats have extraordinary adaptations, including powered #flight, laryngeal #echolocation, #vocal #learning and an exceptional #longevity with unique #immunity and resistance to #cancer! 📸: @DanielWhitby5 (2/n) Image
A #Bat1K team led by @Sonja_Vernes @EmmaTeeling1 @hillermich @TheGeneMyers has just published the raw genetic material that codes for these unique 🦇 adaptations and #superpowers in @nature! #bats #genomics #cool! (3/n) Image
Read 32 tweets
Ahora que están de moda los #anticuerpos y todo el mundo quiere unos por Navidad... Alguna vez os habéis preguntado cómo se producen así de repente cuando te infectas o por qué son efectivos? Os cuento algunas cosas sobre ellos porque es un proceso que MOLA MUCHO⬇️
Los anticuerpos o inmunoglobulinas son producidos por los llamados linfocitos B. Estos son células que se generan en la médula ósea y tienen la capacidad de fabricar anticuerpos. Los anticuerpos son proteínas que se unen de forma específica a los patógenos y los bloquean.
Para que un anticuerpo se produzca tiene que existir un linfocito B que tenga un gen que codifique para ese anticuerpo con la secuencia exacta que haga que se una específicamente a su patógeno.
Read 23 tweets
Daily Bookmarks to GAVNet 6/08/2020-2

greeneracresvaluenetwork.wordpress.com/2020/06/08/dai…

Our Revolution’s Logic - The American Mind

americanmind.org/essays/our-rev…

#revolution #logic
Governments and WHO changed Covid-19 policy based on suspect data from tiny US company | World news | The Guardian

theguardian.com/world/2020/jun…

#suspect #policy #governments #data
Transmission T-030: David Krakauer and Dan Rockmore on out-evolving COVID-19 | Santa Fe Institute

santafe.edu/news-center/ne…

#transmission #SFI #coronavirus
Read 12 tweets
"The live SARS-like coronavirus SL-CoV-WIV1 has been isolated for the first time from bat droppings; and such virus has been confirmed to invade the host cells through the ACE2 of human beings..." ImageImageImage
Bat Severe Acute Respiratory Syndrome-Like Coronavirus WIV1
Encodes an Extra Accessory Protein, ORFX, Involved in Modulation of the Host Immune Response. (2016) #ZhengLiShi #PeterDaszak #EcoHealth
Funding: #NIAID 110964 ImageImageImageImage
In this study, we have developed a fast and cost-effective method
for reverse genetics of coronaviruses by combining two approaches developed by others..As the genomes can be divided into multiple short fragments, mutations can be introduced into individual
fragments easily. ImageImageImageImage
Read 68 tweets
There's a seasonality to many respiratory #viruses. Will #SARSCoV2 [#COVID19] follow a similar pattern? We hope so BUT we don't really know. We know when air is humid / warm ➡️droplets gather more moisture ➡️too heavy to stay airborne / fall more quickly➡️transmission harder. Image
There was a significant correlation between #SARS cases & environmental temperature. A sharp rise or decrease in the environmental temperature related to the cold spell led to an increase of SARS cases because of the possible influence of the weather on the human immune system. Image
Plus the winter season has a profound effect on how human #genes work - this may explain why some illnesses are aggravated in the #winter. During cold, winter months, genes involved with #immunity & specifically #inflammation were more active. nature.com/articles/ncomm…
Read 6 tweets

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