Discover and read the best of Twitter Threads about #genetic

Most recents (24)

Perceptions of #dog breed temperments are ingrained in our culture. Breed #stereotypes play out in dog parks, show up in city ordinances & leases, are celebrated at dog shows, and infuse Hollywood movies... but what if I told you dog temperment doesn't work like that? 1/n Morpheous from the Matrix "But what if I told you"
ANNOUNCING OUR NEW, AT-LEAST-8-YEARS-IN-THE-MAKING-BUT-WHO'S-COUNTING, +FANCY-GENOMICS #DOG temperment PAPER!!!! @UMassChan @broadinstitute @karlssonlab @darwinsarkfnd #ScienceResearch @iaabc 2/n science.org/doi/10.1126/sc… Image of tweet showing April 29 issue of Science with a phot
Before I unpack our findings, I have a conflict of interest to disclose: I AM A CAT PERSON. 3/n
Read 19 tweets
1) Welcome to our new #accredited #tweetorial on the Pathophysiology of #DKD in #T2D: Traditional Teaching and New Insights. Our expert author is Hans-Joachim Anders, MD, @hjanders_hans from @LMU_Uniklinikum of @LMU_Muenchen
2) This #accredited #tweetorial series on the foundations of #kidneydisease #DKD through the lens of #T2D is supported by an independent educational grant from the Boehringer Ingelheim/Lilly Alliance and is intended for healthcare providers.
3) This activity is accredited for #physicians #physicianassociates #nurses #NPs #pharmacists 🇺🇸🇪🇺🇬🇧🇨🇦. Past programs still eligible for credit are at ckd-ce.com. Faculty disclosures are at ckd-ce.com/disclosures/. FOLLOW US for regular programs by expert faculty!
Read 48 tweets
@JorgeCBerny @juliosbernal The graphic of @Conabio summarizes current information on the age of #archaeobotany remains of main #Mesoamerica crops. But it does not discuss or qualify these findings. 1/n
@JorgeCBerny @juliosbernal @Conabio 1) There are relatively few #archaeobotany sites in #Mesoamerica compared with. e.g., #FertileCrescent. So, are current finds representative of the #domestication age of the different #crops ? I doubt it. 2/n
@JorgeCBerny @juliosbernal @Conabio Even the oldest remains (squash, maize) are fully domesticated and do not include a transition from wild to domesticated. So, their domestication could be even older. 3/n
Read 12 tweets
Welcome Back

Immune Responses in Envenomation and Covid

"The powerful influence of Endothelial Cells on immune function has led to hypothesise that immune dysregulation, such as seen in systemic inflammation, might be partially mediated by the endothelium. As venom compounds>
from different species can modulate EC function...this may have important implications in venom-induced systemic inflammation...
Venom from different species can induce EC perturbations, including distortions in cellular function, morphology, cytoskeletal organization, and cell>
viability. Collectively, these actions alter vascular permeability and blood vessel stability
Additionally, snake and spider venoms are highly proinflammatory in EC cultures, commonly provoking the secretion of IL-6, IL-8, monocyte chemoattractant protein-1 (MCP-1/CCL2),>
Read 42 tweets
1/ Here is a review in @Nature by the CovidHGE.com of the human #genetic and immunological determinants of life-threatening #COVID-19 (nature.com/articles/s4158…).
2/ We review what has been learned over the last two years about a simple question: why do about 3% of (#unvaccinated) infected people end up in an ICU with critical C-19 pneumonia when 97% of people control the virus well?
3/ A key conclusion is that inborn errors of, and auto-Abs to type I interferons (IFNs), underlie critical pneumonia in at least 15% of cases, inborn errors being more common < 60 years old and auto-Abs > 70 years old.
Read 11 tweets
Who's ready for another jab in March? Roll up your sleeve (again) for #Pfizer 1.1:

CEO Albert Bourla, Jan 10, 2022: "And we know that the 3, the 2-dose[s] of the #vaccine, offer very limited protection, if any."

#4IR #BiotechEconomy #GeneEditing #mRNA #Crispr

Thread 👇
Bourla con't: "The 3 doses w/ the #booster, they offer reasonable protection against hospitalization & deaths... Now, we are working on a new version of our vaccine, the 1.1 [] that will cover #Omicron as well."

Bourla: "... we are waiting to have the final results. The vaccine will be ready in March, & [] we'll be able to produce it massively."

Yahoo: "I want to quickly talk about the #kids... under 5... the company has said that it's going to need to be a 3-dose vaccine..."
#biotech
Read 6 tweets
This is scandalous.

"#EmergencyUseVaccine" - as response to polio outbreaks - caused by vaccines.

Nov 13 2020: "#WHO today listed the nOPV2 vaccine for emergency use to address the rising cases of a vaccine-derived polio strain in a # of African & E. Mediterranean countries."
"The emergency use listing, or #EUL, is the first of its kind for a vaccine & paves the way for potential listing of #COVID19 #vaccines."

Children in impoverished/destabilized countries are given an oral vaccine - discontinued in wealthy countries decades ago.

#Imperialism
Aired on CBC, 44 yrs ago.

Dr. Jonas #Salk, July 6, 1977:

"We have known now since 1961 in the US, and prior to that in other countries, that the live virus #vaccine for #polio, does cause the disease itself." 👇

Read 8 tweets
#WeekendLecture
#GeneticsAndStroke

#Genetics is involved in several #stroke related conditions, such as small vessel disease #SVD, aneurysms, dissections, cavernomas, and intracranial #hemorrhages

Check this 🧵!
Prepared by @J_Rosales_MD
Edited by @interneurona Image
#Weekendlecture

#Genetic & #SVD
🧬🧠

✅1,5% of cerebral #SVD are #monogenic disorders
✅AR, AD or X-linked
☝🏼Absence of family history doesn't rule out diagnosis because of
👉de novo mutation
👉reduced expression or
👉incomplete penetrance
ahajournals.org/doi/10.1161/ST…
#Weekendlecture

#Genetic & #SVD

When to #suspect?🕵️‍♀️

✅early onset stroke without vascular RFs
✅systemic features and neuroimaging of an specific monogenic disorder
✅consanguinity
✅negative work up for other causes of SVD

👉ahajournals.org/doi/10.1161/ST… Image
Read 15 tweets
"The promise & peril of the Bio Revolution"

"...the world cheered [] that 3 #gene-based COVID19 #vaccines – 1 developed by German #biotech co. BioNTech in collab. w/ Pfizer, another by [] biotech firm Moderna, & a 3rd by [] AstraZeneca – had proved effective in clinical trials."
"But in October, researchers revealed that off-target effects of the #CRISPR-Cas9 #gene-editing tool used to repair a blindness-causing gene in the early stages of human #embryo development often eliminated an entire #chromosome or a large part of it."

#BioengineeringEconomy
"Our deepening knowledge of #biology#genes, #microbiomes, & neural signals – is making it increasingly possible to "engineer life."... #gene drives applied to infectious-disease vectors [] could save many lives, but we may not be able to control them."

#4IR #Biotech
Read 9 tweets
Let's pick out a few key points of the #COVID19 coup

The State should mobilize ALL digital means of control IN PERPETUITY so, should it decide you need to avail yourselves of some 'safety measure', it can 'locate you w/out delay & provide you with "assistance"' 1/n
Such "assistance" can be 'extremely finely targeted - eg, by exploiting #genetic data & #medicalrecords'
Backing this up, you'll be self-reporting your status in real-time via 'connected objects' & imaging cameras allowing #PreCrime - sorry - 'preventative intervention' 2/n
'Teams' can be 'positioned' to isolate people using smartphone tracking.
'Control - if necessary accompanied by sanction' is 'precisely where digital technology' is the 'most EFFICIENT'!
Efficient in the manner that whips, clubs & attack-dogs are 'efficient'.
#COVID19(33) 3/n
Read 16 tweets
2/12/21: Newsweek: "Miraculous #mRNA #Vaccines are only the Beginning"

#mRNA vaccines offer "an early look at how the miraculous tools of the #genetics #revolution will transform our #healthcare & our world over the coming years."

#4IR #biotech

newsweek.com/miraculous-mrn…
"...our Promethean technologies, our moment of triumph could set us on a path to disaster. Of all the species that have ever lived, our single group of hominins now has the capacity to remake all of #biology."

#GeneEditing #4IR #Biotech
The new #vaccines are perfect early examples of this "godlike #technology." ... This approach will soon create a whole new platform for fighting cancers & other diseases, as well as for providing enhancements even more profound than #vaccination."

Human #Experiment w/ #mRNA
Read 11 tweets
2/12/21: Newsweek: "Miraculous #mRNA #Vaccines are only the Beginning"

#mRNA vaccines offer "an early look at how the miraculous tools of the #genetics #revolution will transform our #healthcare & our world over the coming years."

#4IR #biotech

newsweek.com/miraculous-mrn…
"...our Promethean technologies, our moment of triumph could set us on a path to disaster. Of all the species that have ever lived, our single group of hominins now has the capacity to remake all of #biology."

#GeneEditing #4IR #Biotech
The new #vaccines are perfect early examples of this "godlike #technology." ... This approach will soon create a whole new platform for fighting cancers & other diseases, as well as for providing enhancements even more profound than #vaccination."

Human #Experiment w/ #mRNA
Read 10 tweets
't Is hoog tijd dat we eens omkijken en #Reflecteren.
Wat heeft het #COVID-#Beleid van dit #NeoLiberale Kabinet in feite nagestreefd.🤔

En hoe kwamen we zo in de tang van die paar #BioTech #Industrieel #Complex #Miljardairs achter #Pentagon Agency #DARPA & 2001 "#Dark_Winter" 😳
Was de #Anthrax in de poederbrieven aanval in 2001 "#Weapons_Grade" (uit een militair #Biolab zoals Fort Detrick) of uit een andere bron ?

All Roads Lead to 👇👇 #Dark_Winter:

👉thelastamericanvagabond.com/all-roads-lead…👈via @YoureAllDunces
Concerns Amid #Coronavirus Outbreak:

#Pentagon #Agency #DARPA’s decision to classify its controversial #Genetic #Extinction #Research and the technology’s use as a #Biological #Weapon of #War:

thelastamericanvagabond.com/bats-gene-edit… via @YoureAllDunces
Read 5 tweets
The Webinar on "Monoclonal gammopathy and its significance for kidneys" is about to begin!
There is still time to test your knowledge by solving the @ISNeducation quiz ➡️ bit.ly/3j7U5cn
Starting now!
Webinar: "Monoclonal Gammopathy of Renal Significance - Clinical Perspective" with
@arzuvelix and Serhan Tuglular
#ISNwebinar
Welcome Dr @arzuvelix and Dr Serhan Tuglular
Webinar: "Monoclonal Gammopathy of Renal Significance -Clinical Perspective" with

#ISNwebinar
Read 44 tweets
Beware of blue check (w/ few exceptions). #UHN offers ice cream & music in exchange for those willing to take 1st experimental injection - w/ emphasis on #children, 12 yrs of age & up.

UHN Partners:

1. BlueRock
2. CCRM
3. Technion

#4IR #Biotech #Vaccines #CndPoli #tdot
"BlueRock is using its unique cell+gene platform to direct cellular differentiation & #genetically #engineer #cells to create an entirely new generation of cellular medicines in the areas of neurology, cardiology, & #immunology."

#Biotechnology
#Biotech
#UHN partner #CCRM: "A network of academics, industry & entrepreneurs, CCRM translates scientific discoveries into marketable products." CCRM launched in #Toronto on June 14 2011.

The "free" experimental shots will be manufactured by CCRM partner #Pfizer.
Read 5 tweets
Will polygenic risk scores (PRSs) for #cancer ever be #clinically useful?
Our (@clare__turnbull @HoulstonLab_ICR @ICR_London) commentary in @Nature_NPJ is out: nature.com/articles/s4169…
A thread:
1/n
Genome-wide associations studies (GWAS) have identified associations between many #genetic variants and cancer #risk:
nature.com/articles/nrc.2…
3/n
Read 12 tweets
Ultimate victims of media induced fear & politically correct #posturing will be our #children. "hygiene hypothesis: "when exposure to parasites, bacteria, & #viruses is limited early in life, children face a greater chance of [] allergies, asthma, & other #autoimmune diseases..." Image
Dec 10, 2020, Nature: "'#Children are very much adapted to respond — & very well equipped to respond — to new #viruses,' [] even when they are infected w/ #SARSCoV2, children are most likely to experience #mild or #asymptomatic illness." Image
"These children’s #immune systems see the #virus & mounts this really quick & effective immune response that shuts it down, before it has a chance to replicate to the point that it comes up positive on the swab diagnostic test",

Natural #Immunity is not a conspiracy theory.
Read 12 tweets
"These so-called founders will then passively spread the #vaccine to other animals they encounter either by #touch, #sex, #nursing, or #breathing the same air."

thebulletin.org/2020/09/scient…
"For at least 20 years, scientists have been experimenting with such self-spreading #vaccines, work that continues to this day, and which has gained the attention of the US #military."
2020: "We are now poised to begin developing self-disseminating vaccines targeting a wide range of human pathogens, [] decisions remain about how they can be most effectively designed & used to target pathogens w/ a #highrisk of spillover &/or emergence."

nature.com/articles/s4155…
Read 14 tweets
A world record-breaking 261 tomato cultivars were exhibited at @NBGGlasnevin #TTTomFest19! The human race eats ½ its weight in #tomatoes annually. An important crop economically - preserving their valuable #genetic #diversity & #seed #democracy is vital to #future #foodsecurity🍅
1.This thread is about cordon or upright #tomato cultivars. The stunning colour of 'Indigo Rose' gave me the inspiration for the 1st #TotallyTerrificTomatoFestival in 2012. The first naturally-bred, high-anthocyanin tomato, #seed only became available to #gardeners in early 2012>
2.Rosada. The most delicious, disease-resistant, easy and productive variety of cherry/plum I've ever grown. Often bears 70 fruits on long trusses. No longer available as delisted by the politically powerful and greedy #Big4 #seed corporations when they couldn't buy the #patent!>
Read 11 tweets
Daily Bookmarks to GAVNet 11/29/2020 greeneracresvaluenetwork.wordpress.com/2020/11/29/dai…
Direct visualization of quantum dots reveals shape of quantum wave function

phys.org/news/2020-11-v…

#quantum #wave #visualization
Multiple wheat genomes reveal global variation in modern breeding | Nature

nature.com/articles/s4158…

#variation #genetic #wheat #breeding
Read 8 tweets
Did you miss the talk "Panorama of #lupus in 2020?" I did yesterday for @LupusEurope?

No worries, I'm starting a #tweeter #SLE #thread so that you can pick up the slides you're interested in 👍

Check below for the SLIDES ⬇️
Slide #1
Current classification of #Lupus
Slide #2
What is #lupus #SLE
#Lupusawareness
Read 18 tweets
#RareDiseases are not rare. One example is Hyper-IgD Syndrome, an #autoinflammatory / #PrimaryImmunodeficiency disease. Wonderful collaboration extending over 5 years between Kozhikode Medical College, CMC Vellore and CSIR-IGIB as part of the #GUaRDIAN journals.plos.org/plosone/articl… Image
Our #genomic analysis suggests that a few variants account for the majority of the patients with HIDS in South #India with implications in #diagnosis, as well as in the development of cost-effective approaches for #genetic #diagnosis and #screening

@Primary_Immune @MoHFW_INDIA
Read 3 tweets
1-Today is #Thursday – the day of #Jupiter.

#Jupiter is all about expansion,

..#Relationships, the #soul or the #Jeeva and #family and #Ayurveda. (1/25)
2-So, what does #Ayurveda say about man and woman coming together, producing children?

What are the healthy ways to do it?

In that spirit, we will discuss some bit of #Astrology as well as some bit of #Ayurveda. (2/25)
3-This also adds to #गर्भाधान and #Conception threads

..and the role #Astrology and #Ayurveda play in it

..what @shashankupadhy_ has been talking about (3/25)
Read 25 tweets
As a physician, I find it shocking that patients with all diseases are not treated with the same respect and concern as one another. The truth is that someone with a cancer or heart condition has a respected medical disease and something with #obesity does NOT. 1/
The #US nation is now afflicted with #obesity. 42% of Americans suffer from this disease and while the news has covered many stories concerning these facts, the disease continue to rise in its frequency. Individuals continue the same habits that help contribute... 2/
Scientists continue to write endless articles on the subject with basic science that confirms the origins of this disease we know as #obesity. The politicians express great concern, but commit to little action. The insurance industry avoids care as much as possible. 3/
Read 17 tweets

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