Discover and read the best of Twitter Threads about #genobiography
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Today we finally published the genomic analyses of hair locks from world-famous music composer Ludwig van #Beethoven. The #genome offers clues to his health and family history! 🧬💇♂️ @CurrentBiology buff.ly/3YZEVY0 (credits: Beethoven-Haus Bonn; T. Begg)
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@CurrentBiology 8 hair locks attributed to Beethoven = 5 genetic matches + 2 non-matching samples + 1 not conclusive.
Hiller-lock (famous from book & lead poisoning hypothesis) belonged to woman
(credits: Ira F. Brilliant Center for Beethoven Studies, SanJoseStateUni; photo W. Meredith)
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Hiller-lock (famous from book & lead poisoning hypothesis) belonged to woman
(credits: Ira F. Brilliant Center for Beethoven Studies, SanJoseStateUni; photo W. Meredith)
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@CurrentBiology Beethoven’s whole genome was sequenced from one of the matching locks, the Stumpff lock. The ultra-short DNA fragments characteristic of historical hair samples (mean fragment length 29.62 bp) resulted in a 24-fold (!) genome coverage. (credits: Anthi Tiliakou)
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