Discover and read the best of Twitter Threads about #glutamine

Most recents (4)

3VOLUTION of Homo sapien to HOM3OSTASIEN​

by Dmitry Kats, PhD, MPH
scholar.google.com/citations?user…

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A HOM3OSTASIEN represents the evolutionary step forward undertaken by the homo sapien species (among other mammals) to substantially extend and reestablish healthy, fulfilling,… twitter.com/i/web/status/1…
... "inhibition of nuclear de novo NAD+ synthesis reduced the total levels of NAD+ in the cell and mitochondrial energy metabolism, leading to premature cellular senescence"

"nuclear de novo NAD+ synthesis pathway, controlled by H2AX [i.e., GPR109A aka HOM3OSTASIS.com/2022/11/homo-s…twitter.com/i/web/status/1… ImageImageImageImage
... Little do people know, as they don’t care to review the actual literature, that per se, akin to every other cell in the body, as proved in these high-profile journal-published papers (collecting Internet-dust) by the world's most elite investigators (scientists and/or… twitter.com/i/web/status/1… Image
Read 52 tweets
#COVID19 #CVD #MetabolicDisorder and #FlushNiacin (will need equimolar Glutamine w/ it) per Double-Blinded Randomized Placebo-Controlled Clinical Trials Evidence in Humans:

“This meta-analysis involved 2,110 patients with T2DM from 8 RCTs across a wide range of patients’… twitter.com/i/web/status/1…
^ High triglyceride to HDL-cholesterol ratio as a biochemical marker of severe outcomes in COVID-19 patients
clinicalnutritionespen.com/article/S2405-…

Low HDL and high triglycerides predict COVID-19 severity
nature.com/articles/s4159…

Triglyceride/High-Density Lipoprotein Cholesterol Ratio is… twitter.com/i/web/status/1…
^ "In our study, high niacin intake during lifestyle intervention was associated with a larger reduction of liver fat content without affecting insulin sensitivity"

“Among 58 subjects with nonalcoholic fatty liver disease (NAFLD) at baseline, NAFLD resolved in 23 subjects during… twitter.com/i/web/status/1…
Read 15 tweets
My recent DNA #nucleobase etymology thread turned out to be surprisingly popular. So now let's do the amino acids -- #HematologyTweetstory 12. This pretty chart of the #aminoacids is from “BioNinja”: ib.bioninja.com.au/standard-level…
Knowing word origins isn't essential to using terms well, but these histories can be interesting and illuminating. So, while you may not be a bodybuilder💪🏋️‍♂️🏋️‍♀️ who eats amino acids to bulk up, you can read #HematologyTweetstory 12 to build up your “body of knowledge". 😉
Let’s start with #Arginine, “the pirate’s favorite AA” (Arrrr!)🤪, first isolated by Ernst Schulze in Zürich (1886) from lupin seeds. His arginine crystals looked silvery; the Greek word árgyros (ἄργυρος)=silver. Argentina, rich in silver ore, gets its name from the same root./2
Read 23 tweets
Tonight we have a special installment of #MitoMonday as @ClaireBensard hosts a #Tweetorial on her recent paper in @CellMetabolism #LateNightWithTheRutterLab
Can a specific metabolic program provoke a cell to become a cancer cell? Focusing mainly on glucose, with some thoughts on fatty acids, and glutamine, we tested the uncoupling of glycolysis and glucose oxidation to induce the transformation from stem cell to cancer cell. 2/
Long ago, Otto Warburg observed that cancer cells perform aerobic glycolysis, but we didn’t know how a cell could control flux from cytosolic glycolysis to mitochondrial glucose oxidation until the transporter was identified…bit.ly/2RDELqe #MPC 3/
Read 23 tweets

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