@CurrentBiology

@CurrentBiology

@CurrentBiology

@CurrentBiology

Albert Vilella

@AlbertVilella

@broadinstitute

As we see videos in social media of the first $PACB PacBio Revio to enter the @broadinstitute , with the promise of the long-read $1000/genome in place, what does it look like today to set up a Next-Generation Sequencing factory/institute?

https://twitter.com/AlbertVilella/status/1624465272496168965

@broadinstitute

There have been many of these institutes come and go, and probably the @broadinstitute (Cambridge, US) and the @sangerinstitute (Cambridge, UK) are the two referents in historical terms and in their magnitude of achievements in #genomics. So if we take them as an example, what do

we learn from them?
1) They were successful at being early adopters of large-scale Sanger Sequencing.
2) They were very well funded from the get-go, and contributed in large part to the success of sequencing the reference #human #genome in 2000-2001.

Read 46 tweets

Oxford Nanopore

@nanopore

As 2022 draws to a close, we’ve been reflecting on some of the highlights (in no particular order) — you can read the full article here: bit.ly/3IfaKYc, or digest the thread below. Wishing you a happy new year and all the best for 2023! 1/23

The #cancer research community has made huge strides leveraging the unique attributes of #nanopore sequencing to characterise cancer at unprecedented resolution, unlocking previously hidden variation and accelerating research to support human health. nanoporetech.com/cancer-research 2/23

@mdelledon

In May, @mdelledon took a group of scientists into the Gobi Desert to capture small mammals, including bats, to study their microbiome and they set up a genomics lab in a tent. They demonstrated the utility of the MinION in the harsh, off grid and sandy desert environment! 3/23

Read 23 tweets

Ensembl

@ensembl

1/ Are you ready for 🎄🎅Chirstmas #Tweetorial? Whether you need the sequence for a single exon or whole #genome we got you covered! In the spirit of #Christmas, we will use Vitis vinifera 🍇 🍷in our example
#genomics #bioinformatics #Ensembltraining

2/ If you need the sequence of a single #gene, you can search for the gene symbol or ID from Ensembl homepage and click on ‘Sequence’ in the menu on the left

3/ From this page, you can download the sequence of the gene by clicking on the blue ‘Download Sequence’ button just above the sequence display.

Read 10 tweets

Carlos Ribeiro

@RibeiroCarlitos

@Pat_TFrancisco

Excited to share our new manuscript on a novel #neuropeptide family that regulates #feeding across #evolution. Kudos to @Pat_TFrancisco for tackling this challenging project and coming up with the name @marmite . #homeostasis biorxiv.org/content/10.110… 1/22

@TastekinIbrahim

Also kudos to all our collaborators @TastekinIbrahim @EzraGili @fern1_ana @BartDeplancke @albinojorgemai @alisson_gontijo which allowed us to expand the scope of our study and contributed critical insights. It takes a village 2/22

The sequencing of #genomes has been a major milestone in #biology. We have precise maps of the #genome of animals and we think that we know all the major players. Especially the conserved ones which are so important that most animals have them. But is it really like that? 3/22

Read 22 tweets

Cloud Genomics Training

@CloudGenomics

🧵#Bioinformatics and its impact on #healthcare, a THREAD🧵🧵:

#Bioinformatics is the application of #computational techniques to the analysis of #biological data, such as #DNA sequences and #protein #structures.

In #healthcare, #bioinformatics is used to gain insights into the #genetic basis of diseases, and to develop new #diagnostic tests and #treatments.

Read 11 tweets

Cloud Genomics Training

@CloudGenomics

Are you interested in learning about #bioinformatics and working with #genomic data? Here's a detailed #learning path to get you started:

To build a strong foundation in biology, you'll need to learn about:

The #structure and #function of #cells, including the various #organelles and their roles in the cell. This will help you understand how cells work and how they carry out essential functions such as #metabolism and #energy production.

Read 12 tweets

The Jakarta Post

@jakpost

Check out our today’s paper edition on thejakartapost.com/paper/todays-p…

Russian President Vladimir Putin may yet attend next week’s Group of 20 Leaders’ Summit – albeit virtually – President Jokowi suggested on Tuesday. #Putin #G20

Read more: thejakartapost.com/paper/2022/11/…

Indonesia insisted on working to meet global goals through its own interpretations, refusing to make any rhetorical promises while still emphasizing its commitment to climate action. #COP27 #MarufAmin

Read more: thejakartapost.com/paper/2022/11/…

Read 12 tweets

M*m*tch*

@mmtchi

https://twitter.com/mmtchi/status/1555941538777255936

Il paraît que ce post a énervé beaucoup de gens réveillés? Je ne fais qu'analyser et expliquer des études scientifiques, comme depuis 2 ans. Et j'ai encore 2-3 arguments pour en finir avec la théorie de Lanka ou Kaufman que les #virus n'existeraient pas.⏬

https://twitter.com/mmtchi/status/1555941538777255936

Les détracteurs de #virus disent qu'ils "sont confondus avec des #exosomes. Faux & facile à prouver.
Les exosomes, produits par nos cellules, jouent un rôle de messagers. Ils ont une forme sphérique et peuvent #ressembler au virus.
Mais à cause de cette similitude, certains...⏬

Certains affirment que les virus n'existent pas car ils sont confondus avec des #exosomes.
Alors voilà quelques #virus, Ebola, #adénovirus (structure à 20faces), SARSCov2.
En bas voyez des exosomes, à bicouche lipidique. europepmc.org/article/PMC/PM…
Donc non, on n'a rien confondu.⏬

Read 16 tweets

Ensembl

@ensembl

1/ Do you need reference sequence files from #Ensembl? All of the different files available can be confusing. Here’s a thread to help you decide which files you need…🧵

#genomics #bioinformatics #tweetorial #Ensembltraining🧬

2/ Whole-genome reference files for each species in Ensembl can be found on the FTP site 🧑‍🤝‍🧑🐭🐄🐶🐟

👉 ftp.ensembl.org

If you’re studying non-vertebrate species, you’ll need to use the Ensembl Genomes FTP site 🌾🦠🦟

👉 ftp.ensemblgenomes.org

3/ Let’s explore the different directories and files available

Read 16 tweets

Rainbow Conspiracies

@rbwconspiracies

#PROTOKOLL - aufgenommen in der öffentlichen Sitzung des #Landgerichts #Ravensburg, 4. #Zivilkammer, am Donnerstag, 12.03.2015 in Ravensburg

pdfhost.io/v/SQAEREtoi_Pr…

#virus #genome #sequence #genomsequenz

Complete Genome Sequence of a Wild-Type Measles Virus Isolated during the Spring 2013 Epidemic in Germany

Artikel [Englisch]: pdfhost.io/v/GX59BTyJT_Co…

Google Übersetzung: pdfhost.io/v/2WkFtgJo0_Vo…

Source: edoc.rki.de/handle/176904/…

#virus #genome #sequence #genomsequenz

Outbreak of Measles Among Persons With Prior Evidence of Immunity, New York City, 2011

Artikel [Englisch]: watermark.silverchair.com/ciu105.pdf?tok…

Google Übersetzung: pdfhost.io/v/7BgWqor42_Au…

Source: academic.oup.com/cid/article-ab…

#virus #genome #sequence #genomsequenz

Read 3 tweets

Michele Capobianco

@Capobianco2005C

#DueAnniFa, 30-12-2019. Funzionari cinesi indagano sulle cause di un'epidemia di polmonite a #Wuhan! 🤨 #originofcovid
reuters.com/article/us-chi…

#DueAnniFa, 31-12-2019. "#HongKong adotta misure di emergenza mentre una misteriosa polmonite colpisce dozzine di persone nella città cinese di #Wuhan"...🤔
scmp.com/news/china/pol…

@WHO

#TwoYearsAgo, 1-1-2020. "The World Health Organisation (@WHO) said it is in ongoing contact with authorities in #China over an unidentified outbreak of viral pneumonia in the central city of #Wuhan, amid concern it may have been transmitted from animals"🤨
scmp.com/news/china/pol…

Read 19 tweets

Joan Ferrer Obiol

@JoanFerrerObiol

@VizuetaJoel

Our preprint presenting the #genome of the most #endangered #seabird in Europe #Balearic #shearwater is out in #biorxiv

Cristian Cuevas Caballé @VizuetaJoel @meritxellgeno @SeabirdEcology @RiutortLab @JRozasUB

See 🧵👇 1/7

The Balearic shearwater is a Critically Endangered #IUCNRedlist #seabird endemic of the Balearic Islands affected by #introduced mammals and #bycatch in longline #fisheries. Previous studies predict their extinction by 2070! doi.org/10.1111/1365-2…

2/7

Combining #Illumina & #Nanopore data, we present the first high-quality reference genome for the species.

3/7

Read 8 tweets

Nicolas Parisot

@niparisot

@rita_rebollo

Picking up where @rita_rebollo left, we spent a couple of years annotating and analyzing the rest of the rice #weevil #genome (ok, the 15% left after removing repeats)! All info presented here is on the huge Additional file 2 in @BMCBiology doi.org/10.1186/s12915… 1/n

@VargasChavezC

@VargasChavezC and @gabaldonlab performed a comprehensive #phylogenomic analysis of the rice #weevil and found that this insect has a high gene expansion rate when compared to other beetles. 2/n

@INRAE_UMR_BF2I

With the invaluable help of the SymT group from @INRAE_UMR_BF2I we have also reconstructed the #metabolic pathways from both #symbiotic partners. Specific losses of enzymes in the #weevil genome are limited while its #endosymbiont has suffered much more degradation. 3/n

Read 13 tweets

Rita Rebollo

@rita_rebollo

@BMCBiology

⭐️ It is with immense pleasure that we share with you the published #Sitophilus oryzae #genome paper in @BMCBiology doi.org/10.1186/s12915… 1/n

S. oryzae is a #coleopteran capable of destroying entire cereal crops posing a significant threat to the food security of many developing countries. The female #weevil lays ~300 eggs during its lifetime. They develop within the cereal grain until a ~3 day old adult emerges 2/n

Cereal grains are nutritionally poor, and S. oryzae partnered with a gram- bacterium that complements its diet. The bacteria are present within specialized insect cells, called #bacteriocytes. Check here for our latest research on this #symbiosis doi.org/10.1073/pnas.2…. 3/n

Read 20 tweets

Dr. Jacquelyn Jhingree👩🏽‍🔬 #getvaccinated

@Sciency_Jax

@IWS_Network

Many thanks to the awesome ladies at @IWS_Network for the chance to share my #immigrant #womanofcolour #womaninscience👩🏽‍🔬story throughout this week as part of their Voices Without Frontiers program!
iwsnetwork.ca/voices-without…
#IWSvoices #WomenInSTEM

https://twitter.com/IWS_Network/status/1450090254585810951

@IWS_Network

I was born in #Guyana 🇬🇾
➡️ Amerindian name meaning “Land of Many Waters”.
➡️small in size (<800, 000 people), rich in natural resources
➡️only English-speaking country in South America
➡️Diversity of people with amazing cultural mix @IWS_Network #VoicesIWS #WomenInSTEM

@IWS_Network

Genetically I’m Indian - ancestors brought to ‘British Guiana’ from India during colonial times to work on #sugarplantations.

Culturally I’m #Caribbean as #Guyana shares historical and cultural ties with other Anglo-Caribbean countries.

@IWS_Network #VoicesIWS #WomenInSTEM

Read 20 tweets

Kaylee Mueller

@Kaylee__Mueller

@PacBio

Since #genomics classes are starting up again, I thought it would be helpful to make a "@PacBio SMRT Sequencing Resources" thread for you (and your students).

Thanks for the idea @AdamTaran!

1. SMRT Sequencing Overview, Accuracy & Applications
pacb.com/wp-content/upl…

2. The T2T Paper and Publication at a glance

Paper: biorxiv.org/content/10.110…

Publication at a glance: pacb.com/wp-content/upl…

3. What can you do with one SMRT Cell?
pacb.com/wp-content/upl…

Read 6 tweets

Cory Morningstar

@elleprovocateur

2/12/21: Newsweek: "Miraculous #mRNA #Vaccines are only the Beginning"

#mRNA vaccines offer "an early look at how the miraculous tools of the #genetics #revolution will transform our #healthcare & our world over the coming years."

#4IR #biotech

newsweek.com/miraculous-mrn…

"...our Promethean technologies, our moment of triumph could set us on a path to disaster. Of all the species that have ever lived, our single group of hominins now has the capacity to remake all of #biology."

#GeneEditing #4IR #Biotech

The new #vaccines are perfect early examples of this "godlike #technology." ... This approach will soon create a whole new platform for fighting cancers & other diseases, as well as for providing enhancements even more profound than #vaccination."

Human #Experiment w/ #mRNA

Read 11 tweets

Cory Morningstar

@elleprovocateur

https://twitter.com/elleprovocateur/status/1246888952000282624

https://twitter.com/elleprovocateur/status/1246888952000282624

Read 10 tweets

Cory Morningstar

@elleprovocateur

#COVID19 as catalyst for #4IR #biotech experimentation. The fusion of man & machine sought by the depraved. The foray of #gene editing into public realm. You are the subject.

Jan 24, 2019: "Imperial scientists present #vaccine #revolution to world leaders at #WEF in Davos"

January 2021, TIME, double issue. "The #Vaccine #Revolution" has arrived.

TIME - owned by Marc Benioff, CEO/founder of #Salesforce. World Economic Forum Board of Trustees. Inaugural Chair, Forum Centre for the Fourth Industrial Revolution, San Francisco.

#WEF #4IR #Biotech

https://twitter.com/elleprovocateur/status/1246853634819796997

#4IR gene-edited, flu-resistant chickens. Working w/ Roslin Inst. Barclay (Imperial) is using #CRISPR technology - to alter the #genome of a species.

April 5, 2020: One of my most thorough, informative & important threads:

https://twitter.com/elleprovocateur/status/1246853634819796997

Read 4 tweets

GAVNet

@GAValueNetwork

Daily Bookmarks to GAVNet 07/02/2021 greeneracresvaluenetwork.wordpress.com/2021/07/02/dai…

Cognitive Economics: How Self-Organization and Collective Intelligence Works

evonomics.com/cognitive-econ…

#CognitiveEconomics #SelfOrganization #CollectiveIntelligence #groups

THE FREEDOM OF THE PRESS

orwellfoundation.com/the-orwell-fou…

#HumanRights #FreedomOfThePress #GeorgeOrwell #AnimalFarm #BookPublishing

Read 8 tweets

jean-claude perez

@JCPEREZCODEX

@olivierveran

#AFP @olivierveran ==> @JCPEREZCODEX pose une question: "pourquoi avoir traité luc Montagnier de #complotistes en Mai 2020 sur les preuves de #manipulation du #genome
de #SARSCoV2 ? @xazalbert
Mails de Fauci : l'AFP savait-elle pour l'origine du virus ? francesoir.fr/societe-sante/…

@olivierveran

1/3 Pour info nous avertissons par mail @olivierveran du caractère MANIPULE de #SARSCoV2 dés le 26 février 2020, resté sans réponse,
From: Ministère des Solidarités et de la Santé <nepasrepondre@solidarites-sante.gouv.fr>
Date: mer. 26 févr. 2020 à 14:22
Subject: @Le Ministr

2/3 Solidarités et de la Santé a bien reçu votre courriel@.../... DOI : 10.20944/preprints202002.0025.v2
Type : Article
Title : Wuhan nCoV-2019 SARS Coronaviruses Genomics Fractal Metastructures Evolution and Origins
Authors : Jean-Claude Perez.../...
Submission received :

Read 6 tweets

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