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The Pv-aCO2 gap is an easily obtained measure that serves as a marker of impaired cardiac output/tissue perfusion, yet seemingly few of us use it in practice
A short 🧵 on ΔCO2, its potential benefits & some pitfalls
#Hameodynamics #FOAM
A short 🧵 on ΔCO2, its potential benefits & some pitfalls
#Hameodynamics #FOAM
The Pv-aCO2 gradient (ΔCO2) is simply the partial pressure of CO2 in venous blood (mixed or central venous) - the partial pressure of CO2 in arterial blood.
Normal values are ≤ 6mmHg (0.8kPa)
Values > 6mmHg suggest a low CO or impaired microvascular tissue perfusion
Normal values are ≤ 6mmHg (0.8kPa)
Values > 6mmHg suggest a low CO or impaired microvascular tissue perfusion
ΔCO2 is primarily determined by total CO2 production (VCO2), cardiac output (CO) and the complex relationship between pCO2 and total blood CO2 content (CCO2).
It can be conceptualised mathematically using the Fick equation
It can be conceptualised mathematically using the Fick equation
