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1/ Do you know who this man is? 🧵
He’s Fredrick W Mott, an English 🏴surgeon who identified cells with multiple spherical inclusions packed in their cytoplasm in the brains of monkeys with trypanosomiasis.
He’s Fredrick W Mott, an English 🏴surgeon who identified cells with multiple spherical inclusions packed in their cytoplasm in the brains of monkeys with trypanosomiasis.
2/ In the early 1900s, he identified them as plasma cells in inflammation and called them morular cells (Latin morus=mulberry). He was later given the honour of having these cells named after him.
Image credit: doi.org/10.1002/jha2.5…
Image credit: doi.org/10.1002/jha2.5…
3/ It was actually William Russell, a Scottish 🏴physician before Mott, who recognised these inclusions contain immunoglobulin. The individual cytoplasmic inclusions (Russell body) are hence named after him.
Image credit: imagebank.hematology.org/image/4192/rus…
Image credit: imagebank.hematology.org/image/4192/rus…
