Discover and read the best of Twitter Threads about #hepatitis

Most recents (24)

Abro 馃Уpara hacer un recuento de lo que el #A帽o2022 nos dej贸:
1. La aprobaci贸n por la @US_FDA en Noviembre del Tzield (#Teplizumab), un anticuerpo monoclonal anti-CD3 que retrasa la aparici贸n de la #diabetes tipo 1.
2. La publicaci贸n en @ScienceMagazine de la fase 1 del ensayo cl铆nico con la #vacuna eOD-GT8-AS01B para prevenir el #VIH, que indujo la sintesis de #anticuerpos neutralizantes vs el virus, en el 97% de los que fueron vacunados.
3. El #Daxxify una nueva forma de toxina botul铆nica tipo A, cuyo efecto tiene una duraci贸n de hasta 6 meses. El efecto del #botox es de alrededor de 3 meses.
Read 27 tweets
鉀旓笍 Alerta de #Fiebre #Tifoidea

Me han llegado m煤ltiples mensajes de mis pacientes con cadenas de #Whatsapp que alertan sobre varios casos en #Caracas.

As铆 que vamos a explicar un poco. Mi intenci贸n no es alarmar, por el contrario, quiero tranquilizar y educar en prevenci贸n.
La FT es causada por la bacteria #Salmonella typhi. Se transmite por la ingesta de alimentos y el agua contaminados o el contacto estrecho con un infectado. Sus signos y s铆ntomas son:

鈿狅笍 Fiebre
鈿狅笍 Cefalea
鈿狅笍 Dolor estomacal
鈿狅笍 #Estre帽imiento o #diarrea
鈿狅笍 Manchas rosadas en piel
La mayor铆a de las personas que tienen fiebre tifoidea se sienten mejor unos d铆as despu茅s de comenzar el #tratamiento con #antibi贸ticos.

Un 15% de los casos se pueden complicar con #Pancreatitis, #Colcistitis, #hepatitis, #neumon铆a entre otros.

#NO se automedique.
Read 9 tweets
Nog steeds wordt er veel geschreven en veel beweerd over de mogelijke bijwerkingen na vaccinatie met de mRNA-vaccins van #Moderna en #PfizerBioNTech

Wellicht is het goed om een aantal zaken op een rij te zetten. Daarom een glanzend ragfijn draadje.

#COVID19 #vaccin
Belangrijk is te beseffen dat een deel van de bijwerkingen van deze vaccins ook als klinisch symptoom optreedt bij #COVID19.

Dat is ook niet vreemd, gezien het spike-eiwit het meest reactogeen is, en het belangrijkste doelwit van de immuunrespons is.
Zowel het virus als ook het vaccin zetten dit spike-eiwit op de celmembraan van menselijke cellen.

Maar er zijn zeker verschillen: ten eerste heeft het virus een receptor nodig, de welbekende ACE-II-receptor, om de cel binnen te komen.
Read 32 tweets
Se sugiere que el enigma de la #hepatitis aguda grave de etiolog铆a desconocida en #ni帽os lo explica la coinfecci贸n con #adenovirus y virus adenoasociado de tipo 2 (AAV2), y con menos frecuencia el virus del herpes 6 (HHV6)
1/
馃憞
espanol.medscape.com/verarticulo/59鈥
Dos estudios independientes: Un estudio fue dirigido por la University of Glasgow, en Glasgow, y el otro por el Great Ormond Street Hospital de Londres, ambos en Reino Unido.
2/
Los investigadores del estudio de Glasgow usando secuenciaci贸n y PCR, confirmaron la presencia de virus adenoasociado de tipo 2 en el plasma de los 9 casos de hepatitis de inicio agudo y en el h铆gado de los 4 pacientes analizados.
3/
Read 6 tweets
Today is #WorldHepatitisDay2022! To honor it let's talk about Hepatitis B.

The Hep B vaccine is now given at birth, but starting *this year* all adults <60 are recommended to get it.

I talked to the CDC's former viral hepatitis lead Dr. John Ward to understand why 馃У
First, what is viral hepatitis?

Viral hepatitis comprises a few different infections caused by viruses Hepatitis A, B, C, D and E. While A and E mostly cause acute disease, the others including B often lead to chronic infection.

HepB in particular is a lifelong infection.
HepB is harmful because chronic infection is a leading cause of liver cancer.

In the US, between 1-2 MM people have chronic HepB. Most are unaware. And while it travels through body fluids, it's so infectious that transmission can happen through casual contact. (Dr. Ward 猬囷笍)
Read 12 tweets
It's #WorldHepatitisDay!

Bringing #hepatitis care closer to communities and those in need is 馃棟锔 to achieving a hepatitis-free future.

Here are 5鈨 things you should know about viral hepatitis 馃憞
More than 350 million people live with viral #hepatitis, and every 30 seconds, someone dies from hepatitis-related disease including liver failure, cirrhosis and cancer.

Don't wait, get tested 馃憠bit.ly/3cJozjF #WorldHepatitisDay
#Hepatitis A is an infection that can cause mild to severe illness. It is mostly transmitted through ingestion of contaminated food and water or through direct contact with an infectious person.

More info 馃憠bit.ly/3BgIe4Q
Read 11 tweets
Mystery #hepatitis cases in #kids linked to unexpected viral suspect

Two preliminary studies finding #adeno-associated viruses in pediatric hepatitis cases suggest a child's genetic background and other virusesall act in concert
1/
馃憞
science.org/content/articl鈥
Researchers found high adeno-associated virus 2 (AAV2) levels in the blood or liver cells in 24 of 25 children with unexplained hepatitis.

In a group of kids without this condition, almost none had AAV2, even those with #adenovirus.
2/
The young #hepatitis patients were also much likelier to have a #genetic variant that may make their immune systems overreact to viruses.
3/
Read 7 tweets
WHO has issued 馃啎聽tools to help countries respond to unusual cases of severe acute #hepatitis聽(liver inflammation) in children, incl. how to find & report cases.

The detection of cases across 5 WHO Regions is unusual & warrants detailed investigation.

馃搶 bit.ly/3xW9Fxs Image
As of 22 June 2022, 33 countries have reported 920 probable cases:
馃敻cause remains unknown & it is being investigated
馃敻actual number of cases may be underestimated due to limited surveillance in some places
馃敻case count likely to 鈫楋笍聽as more info & verified data become available Distribution of probable ca...
While a few cases of acute #hepatitis in children of unknown cause are reported, every year, some countries indicated that this year this number has been unusually high.

Read 7 tweets
#COVID - epidemic - still raging

#Hepatitis - in children

#monkeypox - spreading throughout UK

#Polio - now found in London

#Cholera - has now re-appeared in EUROPE

Polio spreads from sewage - we are pouring MILLIONS of gallons of untreated sewage into waterways
Look where the UK appears in this chart

RIGHT AT THE BOTTOM

yes, world leading at being LAST, and last well behind the 2nd to last!
DEFINITELY DO NOT GO SWIMMING IN THE UK!
Read 9 tweets
LIVE: Media briefing on #COVID19 & other global health issues with @DrTedros twitter.com/i/broadcasts/1鈥
"Globally, the number of reported #COVID19 cases and deaths continues to decline. This is clearly a very encouraging trend 鈥 increasing vaccination rates are saving lives 鈥 but WHO continues to urge caution. There is not enough testing, and not enough vaccination"-@DrTedros
@DrTedros "On average, about 3/4 of #healthworkers and people aged over 60 globally have been vaccinated. But these rates are much lower in low-income countries. Almost 18 months since the first vaccine was administered, 68 countries have still not achieved 40% coverage"-@DrTedros
Read 24 tweets
#Mesaredonda8 el 4 de junio de 11:30h-13:00h sobre #VIH y #Hepatitis moderada por #M陋Jos茅PenaL贸pez y #MiguelGarc铆adelToro en la que participan los siguientes ponentes:
#AntonioAguileraGuirao del Hospital Cl铆nico Universitario de Santiago de Compostela nos hablar谩 sobre la eliminaci贸n de la #HepatitisC y las nuevas estrategias de diagn贸stico.
#FedericoGarc铆a del Hospital Universitario San Cecilio de Granada nos hablar谩 sobre la infecci贸n oculta del #VIH y lo que se puede hacer para acercarnos al primer objetivo 90.
Read 4 tweets
#25CongresoSEIMC 脷ltima jornada de esta edici贸n de r茅cord de asistencia con mesas muy destacadas, que comienzan en media hora. 隆No te las pierdas!馃斀
#Mesaredonda7: #Covid_19: pasado, presente y futuro. #MesaInternacional #COVID-19 moderada por #JoseMariaMiro y @MariadelMarTom
#MiguelHern谩n de la Universidad de HARVARD analiza como aprender a #prevenir la infecci贸n
usando datos #observacionales
#Mesaredonda8: #VIH y #hepatitis: avanzando en estrategias diagn贸sticas para tratar a nuestros #pacientes. 鈴笍Moderada x #M陋Jos茅PenaL贸pez y #MiguelGarc铆adelToro #AntonioAguileraGuirao del HCU de Santiago nos hablar谩 sobre la eliminaci贸n d#HepatitisC y estrategias de #diagn贸stico
Read 4 tweets
#OutBreak of acute #hepatitis among #children
650 probable cases of acute hepatitis of unknown
aetiology in children have been reported to WHO from 33 countries in 5 WHO Regions between 5 April and 26 May 2022.
1/
who.int/emergencies/di鈥 Image
- Three quarters (75.4%) of cases are 5 years of age.

- Of 156 cases with information on hospital admission, 22 (14.1%) were admitted to an intensive care unit.

Of the 117 cases for which this information was available, 14 (12%) have received a liver #transplant.
2/
- Overall, 181 cases were tested for #adenovirus by any specimen type, of which 110 (60.8%) tested positive. The positivity rate was the highest in whole blood specimens (69.5%).
3/

Table. Classification of reported probable cases per country Image
Read 7 tweets
1.Seit langem habe ich etwas auf meiner Kinder盲rztinnen-Seele, das mal raus muss:
Ein Thread 眉ber #falsebalance in der #Coronapandemie insbesondere in der #Kindermedizin. 脺ber die Rolle der Medien und der #Fachgesellschaften. An einem Vergleich von #FSME mit #Covid bei Kindern.
2.Jedes Jahr aufs Neue: Im Fr眉hjahr kommen sehr viele Eltern zu uns in die Praxis, weil sie ihr Kind gegen #FSME impfen lassen wollen. Soweit so gut. Nat眉rlich haben wir FSME-Impfstoff vorr盲tig, und nat眉rlich impfen wir auch dagegen. Warum ich das erw盲hne?
3.Weil 眉berdurchschnittlich viele ansonsten sehr impfkritische Eltern ihr Kind gegen FSME impfen lassen wollen. Es kommt sogar (regelm盲脽ig) vor, dass Eltern, die ganz bewu脽t nicht gegen Tetanus, Masern, Pneumokokken oder Meningokokken impfen wollen (Impfbuch quasi leer)...
Read 32 tweets
After top 100 updates we will put the top 120 updates , we will start with a thread of top 100 & then move along .
It is a concerning since we may end up seeing either multiple pandemics together or relay race as new organisms try jump into humans ctd)
101/n Whie people like all of us were fighting #Covid , #Hepatitis in kids we all missed how 1284 people got #monkeypox with lethality of 4.5 % ctd)
102/n Interesting paper on efficacy of soaps shows that 1 min hand washing to be effective in cell free virus but not as much in intracellular virus doi.org/10.1016/S0166-鈥
Ctd)
Read 21 tweets
LIVE: Second Plenary meeting at #WHA75 twitter.com/i/broadcasts/1鈥
"Yesterday, I made my remarks on the theme of health for peace and peace for health, which Member States will discuss in the general debate. I want to start today by looking back, to where we have been over the past five years"-@DrTedros #WHA75
@DrTedros "You elected me 5 short years ago, with an ambitious agenda for universal health coverage; health emergencies; women's, children's and adolescents' health; the health impacts of climate and environmental change; and a transformed WHO"-@DrTedros #WHA75
Read 58 tweets
#HEPATITIS aguda, grave y de causa desconocida en ni帽os聽

饾悘饾惈饾悶饾悹饾惍饾惂饾惌饾悮饾惉 & 饾悜饾悶饾惉饾惄饾惍饾悶饾惉饾惌饾悮饾惉聽
Actualizado mayo 21 2022
Abro 馃У
驴Qu茅 est谩 causando la hepatitis en ni帽os?
鉃★笍Todav铆a no se confirma聽
鉃★笍Se est谩n investigando varias etiolog铆as:
-Adenovirus
-Post COVID
-Interacci贸n COVID+otro virus
-Falta de exposici贸n a pat贸genos durante la pandemia聽
-Causas no infecciosas
驴Cu谩les son los s铆ntomas de hepatitis?
鉃★笍Piel/ojos amarillos (71%)
鉃★笍Heces p谩lidas o grises (50%)
鉃★笍V贸mito (63%)
鉃★笍Diarrea (45%)
鉃★笍Fiebre (31%)
鉃★笍Problemas respiratorios (19%)
馃毃Contacta a tu pediatra con la m谩s m铆nima duda
Read 10 tweets
.@CDCgov just did another media briefing on pediatric #hepatitis. They're now investigating 180 cases in US Median age 2, most pre-school age. Haven't identified any new factors, adenovirus 41 still leading suspect.
Here's latest report released 5/18:
bit.ly/3LAieTo
CDC's Jay Butler emphasizes pediatric #hepatitis isn't an "outbreak" per se, as in a spike in new cases. Many of cases being investigated are retrospective. Hard to tell if new cases represent an increase over typical level of severe liver disease in kids (~1500-2000 annually).
Umesh Parashar noted survey of 17 European countries in which 5 reported some increase in pediatric #hepatitis over previous epidemiological trends, but 12 did not. And of 7 non-European countries surveyed, only 1 reported an increase.
Read 5 tweets
The #monkeypox outbreak -- like the pediatric #hepatitis outbreak -- has an element of "seek and you shall find." How many cases of flu-like symptoms with a mild rash or elevated liver enzymes in kids went undetected when people weren't looking for them?

bit.ly/3Pv6fK2
.@mougk is keeping a running tally of confirmed & suspected #monkeypox cases. Strikingly, the 75 cases listed so far are all men in the 20-40 or 30-55 year age range.馃
I'll just add that if #monkeypox does turn out to be a sexually transmitted outbreak among gay men, there's no shame in that. Drawing on their experience with @HIV, the community has done a good job being vigilant about their health & informing partners.
Read 5 tweets
New report on our latest viral foe. I bring up gay men because that's relevant to @pozmagazine readers, but #monkeypox is not solely a "gay disease" & it can be transmitted by any close contact. @Boghuma @ProfKevinFenton @UKHSA @CDCgov
bit.ly/3Pv6fK2
In addition to direct contact with animals, #monkeypox can also be transmitted from person to person via respiratory droplets, saliva & other body fluids and contact with skin lesions or contaminated clothes or bedding.
Like the ongoing鈥攁nd still unexplained鈥攑ediatric #hepatitis outbreak, the new monkeypox cases have spurred much speculation in the press & social media, including questions about whether they might somehow be connected to COVID-19.
bit.ly/3729qri
Read 8 tweets
LIVE: Media briefing on #COVID19 and other global health issues with @DrTedros twitter.com/i/broadcasts/1鈥
"Over the last week, #COVID19 cases have risen in four out of the six WHO regions. Due to testing and sequencing reducing in many countries, it is increasingly difficult to know where the virus is and how it鈥檚 mutating"-@DrTedros
"The Democratic People鈥檚 Republic of Korea has announced, through their state media, their first outbreak of #COVID19, with more than 1.4 million suspected cases since late April"-@DrTedros
Read 31 tweets
HEPATITIS AGUDA INFANTIL de origen desconocido

驴Realmente la est谩 causando el #Adenovirus F41? 馃

Hay algunos puntos a considerar. Va mi opini贸n al respecto馃У馃憞馃徏

1/15

#HepatitisAgudaInfantil
Hace un mes (15Abr22) nos enteramos de que Reino Unido 馃嚞馃嚙 estaba reportando un incremento inusual en los casos de #hepatitis de origen desconocido en pacientes pedi谩tricos, especialmente en l@s m谩s j贸venes

Despu茅s otros pa铆ses empezaron a reportar lo mismo (tot: 169 casos)

2/15
La presentaci贸n cl铆nica, es decir, la manera en la que el personal m茅dico identifica la enfermedad馃懇馃徎鈥嶁殨锔, es una #HepatitisAguda (el surgimiento r谩pido de inflamaci贸n en el h铆gado) con una elevaci贸n muy pronunciada 馃搱 en los niveles de prote铆nas provenientes de ese 贸rgano鹿

3/15
Read 16 tweets
1/
Hace ya 5 semanas que @ECDC_EU activ贸 la alerta por los casos de #hepatitis agudas graves en ni帽os de causa desconocida

驴Qu茅 hay de nuevo?

馃搱 M谩s de 400 casos en estudio
馃搲 Ca铆da de casos en 馃嚞馃嚙
馃 Informaci贸n sobre la posible causa
鈦夛笍 Muchas preguntas

#livertwitter #COVID19
2/
Antes de seguir puedes revisar donde est谩bamos hace unas semanas

馃憞馃憞馃憞

3/
El n煤mero de casos compatibles ha aumentado, en parte porque se han ampliado los criterios de b煤squeda, era esperable:

馃嚞馃嚙 163
馃嚜馃嚭 106
馃嚭馃嚫 109

Llama la atenci贸n el "bajo" n煤mero de casos sospechosos (para la poblaci贸n) de la UE y USA 馃

#livertwitter
Read 20 tweets
Las teor铆as del origen de la #hepatitis infantil
Abro hilo
1. Un nuevo virus, o una nueva forma de un virus ya existente.
Se ha asociado a una infecci贸n por adenovirus 41, pero aun falta informaci贸n para confirmar esto y saber por qu茅 ha afectando de esa forma el h铆gado
2. Una co-infecci贸n, es decir una infecci贸n simultanea del adenovirus con el SARS-COV2.
Lo que va en contra de ests teor铆a es la ausencia de infecci贸n aguda por #COVID19 en la mayor铆a de los casos
Read 6 tweets

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