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Spherocytes don’t jiggle jiggle, like normal biconcave RBCs b/c of defects in membrane proteins (ankyrin-1 band 3)
They are smaller in diameter, hyperchromic, & lack central pallor.
HS is the leading cause of Coombs-neg hemolytic anemia requiring transfusion in neonates.
They are smaller in diameter, hyperchromic, & lack central pallor.
HS is the leading cause of Coombs-neg hemolytic anemia requiring transfusion in neonates.
To learn about testing for HS check out this great post by @AaronGoodman33 👇🏼👇🏼
💡💡And for even more learning, check out
@rabihmgeha diagnostic work up for #hereditaryspherocytosis 👇🏼👇🏼
@rabihmgeha diagnostic work up for #hereditaryspherocytosis 👇🏼👇🏼
