Discover and read the best of Twitter Threads about #hhv6

Most recents (4)

"@BhupeshPrusty Prusty thinks #MECFS originates in early childhood, when most people are infected by human betaherpesvirus 6B (HHV-6B), which causes a mild illness lasting a few days. “Afterwards, the virus stays in our body for the rest of our lives,” 🧵

archive.vn/2023.03.04-224…
says Prusty. Later in life, the virus can become reactivated – and it is this that Prusty and some others believe causes ME/CFS.

In a 2021 study, Cliff and her colleagues took monthly saliva samples from 30 people with #MECFS and 14 people who didn’t have the condition. Those 🧵
with #MECFS had higher levels of HHV-6B and another herpes virus, HHV-7, than those without. In people whose symptoms fluctuated over time, more severe symptoms were associated with higher levels of HHV-6B and HHV-7, than those without. In people whose symptoms fluctuated 🧵
Read 8 tweets
A new publication by Simmaron!

“Potential molecular mechanisms of chronic fatigue in #LongCOVID and other viral diseases”
A hypothesis-driven review article demonstrates a diverse range of inflammatory & metabolic pathways responsible for fatigue of viral origin. 1/5 Image
These 5 viruses (#HHV6, #Powassan, #EBV, #HIV, #SARS-CoV2) trigger unique immunological reactions, yet lead to similar inflammation + muscle fatigue. Examining these pathways can bring light to possible treatments for #mecfs #longcovid.

rdcu.be/c48cR 2/5
#HHV6
Immunosuppression, autoimmune reaction (IgM abs), microglial activation and production of #cytokines, Amyloid-beta, OPC immuration, demyelination 3/5
Read 5 tweets
So I’ve decided to #interview many of the researchers/MDs I collaborate with or know as friends. That’s b/c most have an incredible base of knowledge and unique skillsets that need to be shared with a wider audience!
2/ I started w/ Dharam Ablashi, who co-discovered the #virus human #herpesvirus 6 (HHV6) along w/ Robert Gallo in the 1980s. Here is the #interview, which ended up documenting one of the most fascinating + informative conversations I’ve ever had: microbeminded.com/2020/06/28/int… Image
3/ Overall, Dharam and I talked abt his own extensive research on #HHV6, challenges he faced in moving the work forward, plus his opinion on key studies that clarify the pathogenic role of HHV6-A + HHV6-B in neurological disorders such as #MS, #epilepsy, #ME/CFS and #Alzheimer’s
Read 3 tweets
Die übliche Darstellung der Verläufe von #COVID19 ist zu zweidimensional: am Ende ist man NICHT entweder gesund oder tot.

Viele Pathogene können zu schweren chronischen Leiden wie #MECFS führen: Diese Patienten überleben den akuten Infekt, verlieren aber trotzdem ihr Leben. 1/
Eine 2006 in Australien durchgeführte Studie hat gezeigt, dass ganze 11% der an Pfeifferschem Drüsenfieber, Q-Fieber oder Ross-River-Fieber Erkrankten sechs Monate nach der akuten Infektion an #MECFS litten. 2/

ncbi.nlm.nih.gov/pmc/articles/P…
Nach dem Ausbruch von SARS in 2003 entwickelten viele Patienten ein sog. "post-SARS-Syndrom", das symptomatisch weitgehende Übereinstimmung mit #MECFS aufweist. 3/

bmcneurol.biomedcentral.com/articles/10.11…
Read 108 tweets

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