Discover and read the best of Twitter Threads about #highresolution
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How do you image the large and the small at the same time? We developed new 🔬 technology to image centimeter-scale specimens - including whole mouse brains 🧠- with diffraction-limited resolution and without sectioning. #mesoscale #imaging
biorxiv.org/content/10.110…
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biorxiv.org/content/10.110…
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ExA-SPIM is a technology based on innovations in (1) tissue processing and (2) large-scale microscopy 🔬. Our team developed new methods for expansion for microscopy (ExM) of large tissue volumes. #teamscience #expansionmicroscopy
protocols.io/view/whole-mou…
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protocols.io/view/whole-mou…
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By combining ExM with a new SPIM system based on technologies from electronics metrology, ExA-SPIM pushes past the volumetric imaging barrier 🚧 that constrains previous imaging approaches. (inspired by recent plot from @Daetwyler_St, @RetoPaul) #lightsheet #microscopy
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