Discover and read the best of Twitter Threads about #hippocampal
Most recents (3)
Finally published! 🎉 reposting d/t broken link in first thread:
Early-life exercise primes the murine neural epigenome to facilitate gene expression and hippocampal memory consolidation | Communications Biology nature.com/articles/s4200…
Early-life exercise primes the murine neural epigenome to facilitate gene expression and hippocampal memory consolidation | Communications Biology nature.com/articles/s4200…
Our study discovers both new and well-known #geneexpression programs involved in #hippocampal memory following #adolescent #exercise, and also investigates two #epigenetic modifications in these mechanisms (open access @CommsBio)
We asked which genes are altered following aerobic exercise (voluntary wheel running) in adolescent hippocampus, using a transgenic mouse & technique we developed for simultaneous sequencing of the epigenome and translatome in excitatory neurons.
Are there any changes in #brain #structure during the first year following #trauma #exposure? Is there a difference between individuals who develop #chronic #PTSD and those who #recover? A quick thread about our work published today in @molpsychiatry📜🧠🧵
nature.com/articles/s4138…
nature.com/articles/s4138…
Reduced #hippocampus and #amygdala volumes have been repeatedly documented in #PTSD patients. But do they reflect a #pretrauma vulnerability trait or #postexposure stress-induced atrophy?
To answer this question, we examined the association between #longitudinal #volumetric #changes of the hippocampus and the amygdala, as well as their #key #subregions, and #PTSD #symptom #trajectories during the first #14months following #trauma exposure. 
Hello #dendrites friends! Check out our new paper, published at @NatureComms : "Challenging the point neuron dogma: FS basket cells as 2-stage neural networks. nature.com/articles/s4146…
Briefly, we predicted through #computational simulations that the #dendrites of #Fast_spiking #interneurons in #Hippocampal #CA3 and #PFC areas come in two #nonlinear flavors: Supralinear and sublinear!
This bimodal nonlinear behavior is determined by differences in the morphology (volume) of the dendritc branches. These differences can causally enable or prohibit the existence of #sodium_spikes. Interestingly, both types coexist in all model neurons tested!
