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THIS 👉 #Mitochondria play a role in helping white blood cells target human #pathogens☝️Below, mitochondria-derived vesicles delivered #antimicrobial reactive oxygen species to control phagosome-localized S. aureus (a #bacterial infection)
So let’s add #mitochondria to the growing list of human organelles/proteins/pathways recently shown to have #antimicrobial activity 👉 Other compounds already on that list include #amyloid beta, alpha-syn, PrP, #HMOs etc☝️More context here: microbeminded.com/2018/12/30/myf…
Also #mitochondria are derived from #bacterial ancestors, and can become infected by a range of viral/bacterial #pathogens 👉 Suggests mitochondria’s antimicrobial activities may be defense mechanisms that stem from their #evolutionary history as a free-living organisms
