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Our study “An in vitro model for anteroposterior organisation during human development” is out! nature.com/articles/s4158… @nature @Cambridge_Uni @_Hubrecht A summary: (1/10)
In this study, we used human Embryonic Stem Cells that we disassociate and resuspend together into small, spherical 3D aggregates. Remarkably, these are able to spontaneously break symmetry, and, over 3 or 4 days, they elongate along a single anterior-posterior axis (2/10) 
Using a triple-coloured reporter of the 3 germ layers, we saw that these aggregates had polarised expression of Brachyury at the most distal end, and they express all three fluorescent reporters in an organised manner (3/10)
