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In our new paper @eLife we show how TF Sox9 controls #neurogenesis and #gliogenesis during neocortex development. Work driven by Ayse Guven, former PhD student #Huttnerlab @mpicbg 1/3 elifesciences.org/articles/49808
Previous work showed that components of the extracellular matrix are important for proper brain development. Ayse found that the transcription factor Sox9 drives the expression of ECM components in neural progenitors. 2/3
Manipulating the expression of Sox9 in ferret and mouse we showed that Sox9 orchestrates several fundamental processes during brain development: progenitor #proliferation, #neurogenesis and #gliogenesis 3/3
