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THREAD and my infographic of the #TTM2 trial
#OHCA patients were randomised to #TTM at 33°C or normothermia (<37.8°C) with early fever treatment.
➡️ Mortality and poor neuro outcome at 6 months were not lower in the hypothermia group.
🔗 nejm.org/doi/full/10.10… #FOAMcc
#OHCA patients were randomised to #TTM at 33°C or normothermia (<37.8°C) with early fever treatment.
➡️ Mortality and poor neuro outcome at 6 months were not lower in the hypothermia group.
🔗 nejm.org/doi/full/10.10… #FOAMcc
Guidelines recommend selecting and maintaining a constant target #TTM between 32 and 36 °C in comatose post-cardiac arrest patients to prevent hypoxic-ischemic brain damage.
(strong recommendation, moderate-quality evidence). #FOAMcc
(strong recommendation, moderate-quality evidence). #FOAMcc
Two RCTs published in 2002 showed an improved survival and neurologic outcome in patients resuscitated from OHCA of presumed cardiac cause and shockable rhythm who underwent hypothermia at 33°C. #FOAMcc
