Discover and read the best of Twitter Threads about #icudata
Most recents (4)
NEXT : @AriErcole
Association is not necessarily a causation
RCTs are thought of as "gold standard" for a good reason.
"Randomisation" eliminates influences of confounders.
- allows "causality" inference.
Association is not necessarily a causation
RCTs are thought of as "gold standard" for a good reason.
"Randomisation" eliminates influences of confounders.
- allows "causality" inference.
@AriErcole RCTs require relatively little prior knowledge.
But
"DO WE HAVE ASSURANCE OF THIS" ?
we try to "by having a inclusion criteria"
🧐 we can only control what we know
RCTs have limitations - dont really imply causality absolutely.
@ESICM #datascience #ai #ml #icudata #RCT
But
"DO WE HAVE ASSURANCE OF THIS" ?
we try to "by having a inclusion criteria"
🧐 we can only control what we know
RCTs have limitations - dont really imply causality absolutely.
@ESICM #datascience #ai #ml #icudata #RCT
Now Harm-Jan De Grooth "Understanding Bayesian Analysis"
- more specifically "Bayesian Trial analysis"
@ESICM #datascience #ai #ml #icudata #bayesian
- more specifically "Bayesian Trial analysis"
@ESICM #datascience #ai #ml #icudata #bayesian
@ESICM Trials are now using Bayesian analysis or at least in secondary analysis.
pubmed.ncbi.nlm.nih.gov/30347031/
But also NEJM IL-6 in covid - purely bayesian analysis.
pubmed.ncbi.nlm.nih.gov/30347031/
But also NEJM IL-6 in covid - purely bayesian analysis.
NEXT Adaptive and Platform trial designs by @Lennie333 #datascience #ai #ml #icudata
#LIVES2022 #ventilation
@ESICM
we assume "large effect sizes" in ICU trials
#LIVES2022 #ventilation
@ESICM
we assume "large effect sizes" in ICU trials
@Lennie333 @ESICM this is because otherwise we will need large "n" and long time for trials.
e.g., anti-hypertensives - you dont want to test one drug at one dose. you want to test a range of doses and a range of duration.
third-thing : we struggle to find a end-point especially in critical care
e.g., anti-hypertensives - you dont want to test one drug at one dose. you want to test a range of doses and a range of duration.
third-thing : we struggle to find a end-point especially in critical care
@Lennie333 @ESICM huge effort doing RCT but we use "mortality" yes/no as a very binary endpoint. For patient, length of stay, quality of life after d/c important end points beyond survival.
in RCT, we cant learn whilst the trials are still running. in classic RCT.
in RCT, we cant learn whilst the trials are still running. in classic RCT.
NEXT:Interfacing ICU data Nicolas Bennet
- Nicolas was very pleased to hear Chris Sauer(earlier speaker) advocating use of 2 -data set at least
@ESICM #criticalcare #ai #ml #icudatasets
- Nicolas was very pleased to hear Chris Sauer(earlier speaker) advocating use of 2 -data set at least
@ESICM #criticalcare #ai #ml #icudatasets
@ESICM eth-mds.github.io/ricu/
showcasing this R dataset
starting with
'r'
> library(ricu)
> lact (loaded all lactate data)
'r'
showcasing this R dataset
starting with
'r'
> library(ricu)
> lact (loaded all lactate data)
'r'
@ESICM NEVER THOUGHT THAT I would be tweeting code in an ICU conference :)) @ESICM #datascience :P #datascience #LIVES2022
