Discover and read the best of Twitter Threads about #igM

Most recents (5)

H pylori #tweetorial for resistant H pylori
#AGA released CPU in 4/21 revisiting topic of resistance/treatment failures, not a guideline, but the expert opinion @BradSpellberg loves! (1/x)
gastrojournal.org/article/S0016-…
@ABsteward @RushCCH_ID #MedEd #medtwitter #idtwitter
As GN bacteria go, it's an interesting bug:
Highly motile, curved, GNR, #Urease-positive, catalase-positive, oxidase-positive
Related to Campylobacter, for family fun
Nice crossover with our #Gastroenterology colleagues, eh #IDtwitter and @IDSAInfo
(2/x)
GN, and as such should be sensitive to most #antibiotics that target GN with pretty good susceptibilities over time for:
#amoxicillin #tetracycline #aminoglycoside #nitroimidazole #macrolide
(3/x)
Read 25 tweets
#Class__Switching

Looking at antibody class switching.
1/ All B cells have the immunoglobulins IgM and IgD on their cell surface. The DNA contains both the information to create these two classes of immunoglobulins. They will be produced in equal amounts during the B cell development.
2/ Once a B cell is activated toward a pathogen, it will begin to secret immunoglobulins (antibodies) in the form of the IgM. This is the only thing it is able to create and secret at this point.
Read 22 tweets
Ein Thread: Warum man mindestens die ersten 2 Wochen nach der #Impfung noch sehr vorsichtig sein sollte und warum die Ausdehnung des Impfintervalls auf 6 Wochen für #mRNA Impfstoffe unter den derzeitigen Umständen sinnvoll ist.
Der Aufbau eines Schutzes braucht Zeit...1/n
Nach der Infektion bzw Impfung beginnt das Immunsystem zu arbeiten, es kommt zur Ausbildung spezifischer #Antikörper gegen #SARSCoV2, zuerst #IgM und dann langlebige Antikörper der Klasse #IgG. In der Abbildung sieht man die Bildung der IgG Antikörper nach einer Infektion...2/n Image
Ca 2-3 Wochen nach Infektion sind diese Antikörper nachweisbar (die zeigen übrigens auch bei schwach PCR positiven an, dass eine Infektion vorlag). Nach ca 30 Tagen ist die Konzentration (Titer) am höchsten und dann fällt die Konzentration über Monate hinweg wieder ab...3/n
Read 11 tweets
Ahora que están de moda los #anticuerpos y todo el mundo quiere unos por Navidad... Alguna vez os habéis preguntado cómo se producen así de repente cuando te infectas o por qué son efectivos? Os cuento algunas cosas sobre ellos porque es un proceso que MOLA MUCHO⬇️
Los anticuerpos o inmunoglobulinas son producidos por los llamados linfocitos B. Estos son células que se generan en la médula ósea y tienen la capacidad de fabricar anticuerpos. Los anticuerpos son proteínas que se unen de forma específica a los patógenos y los bloquean.
Para que un anticuerpo se produzca tiene que existir un linfocito B que tenga un gen que codifique para ese anticuerpo con la secuencia exacta que haga que se una específicamente a su patógeno.
Read 23 tweets
Senta que lá vem história:
Qual a razão numa pandemia como esta de #COVID19 causada pelo novo #coronavirus para se fazer testes em massa? Siga o fio... 🧗‍♀️🧗‍♂️
A primeira razão p/ ter em larga escala o teste da #PCR (do Inglês polymerase chain reaction test) é poder confirmar de imediato o diagnóstico de portadores de #COVID-19 É determinar quarentena, isolamento social e uma melhor observação evolutiva tanto do doente dos contactantes!
A outra razão importante sobre o #PCR é poder avaliar o material genético do #SARSCoV2 que está naquele momento circulando na comunidade e avaliar por exemplo a existência de mutações na região e/ou país.
Read 6 tweets

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