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Today we publish a paper in @ScienceMagazine that expands nanopore readings to the proteome:
a nanopore-based scanner to read off PROTEINS at the single-molecule level! šŸ¤©

Awesome experiments by postdoc Henry Brinkerhoff of our #CDlab, with MD simulations of @aksimentievLab

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@ScienceMagazine @aksimentievLab Hereā€™s the link to this paper in @ScienceMagazine entitled ā€œMultiple re-reads of single proteins at single-amino-acid resolution using nanoporesā€: science.org/doi/10.1126/scā€¦

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@ScienceMagazine @aksimentievLab Principle reminds of nanopore DNA sequencing: we draw a peptide through a nanopore with a helicase walking on a lead DNA strand, and then read off ion current step signals as amino acids are blocking the pore.

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