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1/
Why is the chancre of primary syphilis painless?
Why don't we see syphilitic pneumonia?
Was mercury effective against syphilis?
These and other questions will be covered in this thread, a follow-up to a talk given at #IM2019, alongside @AdamRodmanMD
Why is the chancre of primary syphilis painless?
Why don't we see syphilitic pneumonia?
Was mercury effective against syphilis?
These and other questions will be covered in this thread, a follow-up to a talk given at #IM2019, alongside @AdamRodmanMD
2/
Let's get right to Q1: Why do think the chancre of primary syphilis is painless?
Let's get right to Q1: Why do think the chancre of primary syphilis is painless?
3/
In 1975, Ovcinnikov and Delektorskij identified T. pallidum within the peripheral nerves deep to the chancre of primary syphilis.
One hypothesis is that involvement of these sensory nerves leads to decreased sensation and thus the painless chancre.
ncbi.nlm.nih.gov/pubmed/1092423
In 1975, Ovcinnikov and Delektorskij identified T. pallidum within the peripheral nerves deep to the chancre of primary syphilis.
One hypothesis is that involvement of these sensory nerves leads to decreased sensation and thus the painless chancre.
ncbi.nlm.nih.gov/pubmed/1092423
