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Different cell types in the brain have their own connectivity rules and patterns. In a recently published study, our #neuroscience researchers took a deep dive into the connectomics of an important but enigmatic cell type, the chandelier cell. ๐Ÿงต1

๐Ÿ“„ elifesciences.org/articles/73783
๐Ÿ”ฌ ๐Ÿ’ป Using large-scale #electronmicroscopy with automated segmentation, we mapped the complete axo-axonic input onto pyramidal neurons (1,929 synapses in total, 1,127 from chandelier cells) in a volume of layer 2/3 of mouse visual cortex. #ImagingTheFuture #BrainMapping๐Ÿงต2
By completely reconstructing the presynaptic chandelier cells, we found a novel principle of connectivity, where a group of interneurons are essentially interchangeable, but their postsynaptic targets individually regulate the amount of input they receive from the population. ๐Ÿงต3
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