Discover and read the best of Twitter Threads about #imatinib

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Basic research by Dr. Brian Druker @OHSUKnight in the 1990s contributed to the development of #imatinib (Gleevec), a landmark drug that has improved the outcomes of patients with #chronicmyelogenousleukemia. cancer.gov/research/progr… #NothingWillStopUs Photo of Dr. Brian Druker
He discovered that a compound called STI-571 (a.k.a #imatinib) specifically inhibits growth and tumor formation by #leukemia cells expressing BCR-ABL (a fusion oncoprotein that drives #chronicmyelogenousleukemia) in an @theNCI funded @NatureMedicine study. nature.com/articles/nm059…
Based on these findings, Dr. Druker et al. tested #imatinib in a phase 1 #clinicaltrial. They found that the drug was well tolerated and an effective treatment against #chronicmyelogenousleukemia in patients with late-stage disease. nejm.org/doi/10.1056/NE… #NothingWillStopUs
Read 6 tweets
Fuentes de prensa indican que La Casa Blanca evaluaría el suspender temporalmente disposiciones de #propiedadintelectual sobre las #vacunas #Covid-19. Tema que amerita hilo 🧵 tinyurl.com/h7h8434m
Al respecto la prestigiosa revista Nature indicó, en su editorial del 30 de marzo, que este sería un movimiento en la dirección adecuada e insta a otros gobiernos a avanzar en esa dirección. nature.com/articles/d4158…
Esto implicaría un giro en la habitual posición del Gobierno de #EEUU como uno de los principales promotores de las medidas de #Propiedadintelectual en el sector farmacético.
Read 11 tweets

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