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#Immunoglobulins

Basics of Antibody Structure and B cell maturation.
1/ Immunoglobulin means “Immune Protein”. This is what we call the proteins produced by the B cells. When these immunoglobulins are embedded into the B cell membrane, they are called the B cell receptor (BCR).
2/ When they are secreted out of the mature B cell, they are called Immunoglobulins or antibodies. The term Immunoglobulin will be abbreviated as Ig.
Read 19 tweets
Some have suggested that detection of #SARSCoV2 antibodies could be a basis for an “immunity passport” / “risk-free certificate” that will enable individuals to return to work. Currently, there is no evidence those who have recovered from #COVID19 are protected from re-infection.
Immunity to a pathogen through natural infection is a multi-step process that usually takes place over 1-2 weeks. The body responds to a viral infection immediately with a non-specific innate response: macrophages, neutrophils, dendritic cells slow the progress of the virus.
This non-specific response is followed by an adaptive response i.e. body makes #antibodies that specifically bind to the #virus. These #antibodies are proteins called #immunoglobulins. The body also makes T-cells that recognize & eliminate other cells infected with the virus.
Read 8 tweets

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