Discover and read the best of Twitter Threads about #immunosenescence

Most recents (3)

We’re proud to announce the publication of our successful Phase 3 trial of NanoFlu™, our seasonal quadrivalent Nanoparticle #Influenza #Vaccine (#qNIV) candidate, in @TheLancetInfDis. Let’s dig into why it matters: thelancet.com/journals/lanin…

Thread:
According to @CDC, “on average, about 8% of the U.S. population gets sick from #flu each season.” There is an urgent need for improved flu #vaccines, particularly for older adults (>age 65), who bear higher disease burden. cdc.gov/flu/about/keyf…
Coverage of existing flu vaccines is >60% in the US, but recent flu seasons have shown vaccine effectiveness may be just 10-13% for one virus strain (A/H3N2) in older adults. ncbi.nlm.nih.gov/pmc/articles/P…
Read 25 tweets
Covid19 enfeksiyonuna yakalanan çoğu kişinin vücudu bozuk bir saat gibi çalışır.

#immunosenescence
Özellikle 45 yaş üzerinde Covid19 sebebiyle ölümlerin daha fazla olmasının sebebi olabilirmi?

İmmünosens terimi, artan yaşla birlikte bağışıklık sisteminin performansındaki kademeli düşüşü tanımlar.
Yaşlanma sırasında doğuştan gelen ve adaptif immün savunmada değişiklikler vardır. Bu değişiklikler klinik ortamda kolayca tespit edilebilir. Zayıflayan bağışıklık tepkisi çok sayıda hastalığa yol açabilir.
Read 21 tweets
📣 #THREAD: COVID-19 could be a double whammy for older people -- they're more likely to die from it and they might be less likely to respond to a vaccine. This might be due to "#immunosenescence" and "#inflammaging", as I describe in my latest story: nationalgeographic.com/science/2020/0…
Surprise! If you are reading this tweet and past puberty, your thymus gland -- which harbors the T cells that help train the body to make protective antibodies against new viruses (and respond to vaccines) -- is already shrinking: nationalgeographic.com/science/2020/0…
Almost a century ago, Edith Boyd helped confirm that the thymus shrinks with age. Boyd was an anatomist who combed through data from 10,000 autopsies collected at the University of Minnesota and compared them to similar findings from European scientists: nationalgeographic.com/science/2020/0…
Read 12 tweets

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