Discover and read the best of Twitter Threads about #infections

Most recents (10)

📢🎉The work of #Bat1K is featured on the cover in the latest issue of @nature: “Six reference-quality #genomes reveal evolution of #bat adaptations” 🦇🧬 #bats Our thread 👇 on the paper:nature.com/articles/s4158… 📸: Olivier Farcy(1/n) Image
📢Have you ever wondered how 🦇 manage to do what they do? #bats have extraordinary adaptations, including powered #flight, laryngeal #echolocation, #vocal #learning and an exceptional #longevity with unique #immunity and resistance to #cancer! 📸: @DanielWhitby5 (2/n) Image
A #Bat1K team led by @Sonja_Vernes @EmmaTeeling1 @hillermich @TheGeneMyers has just published the raw genetic material that codes for these unique 🦇 adaptations and #superpowers in @nature! #bats #genomics #cool! (3/n) Image
Read 32 tweets
Cool new study which found that a range of #pathogens (some capable of long-term persistence in tissue + #blood) upregulate expression of the cell surface protein CD47 in the host cells they infect as an #immune evasion strategy
2/ I fact, upregulation of CD47 is a very smart survival strategy by such pathogens, b/c it interferes w/ the host innate immune response that is normally supposed to identify, target and kill them!
3/ Specifically the team found that upregulation of CD47 by the pathogens under study slowed uptake of dead/#infected cells by the #immune system, including the downstream activity of #antigen presenting cells that are needed to recognize pathogens in the first place
Read 10 tweets
Daily Bookmarks to GAVNet 6/17/2020-2

greeneracresvaluenetwork.wordpress.com/2020/06/17/dai…

The Information Age Is “Weaponized” - Extra Newsfeed

extranewsfeed.com/the-informatio…

#weaponized #information
If 80% of Americans Wore Masks, COVID-19 Infections Would Plummet, New Study Says | Vanity Fair

vanityfair.com/news/2020/05/m…

#coronavirus #infections #masks
Opinion | ‘This You?’ Is Twitter’s New Meme. Here’s What It’s All About. - The New York Times

nytimes.com/2020/06/09/opi…

#accountability #meme
Read 10 tweets
Missed Friday, but I'm back with the daily #chart, with commentary by @reutersMikeD in the thread below. This one is global #COVID19 cases versus the #VIX #volatility index. Volatility has shot up in the last few days, amid a rising number of #infections in Beijing and the U.S.
It shows there really is still nothing more important for macro markets than the trajectory of the virus and shows super sensitivity to any rise infections associated with economies reopening - there was always likely to be some quid pro quo between people returning to work/...
...school/shops/big gatherings and rising infections - we now face the test of this over the coming weeks and market volatility gauges more than cash indices are the real relfection of that trepidation. Whatever governments do to respond may be trumped by a rise in public fear of
Read 7 tweets
1/ Q: Can people get re-infected with SARS-CoV-2?

A: While some individuals test positive again after recovering from #COVID19, a new study suggests that these #infections are NOT active.

More about how the findings below
2/ Tests used to determine if someone has #COVIDー19 detect the presence of the virus' genetic material.

However, they do not indicate whether a person has an active infection: i.e. actively shedding virus capable of infecting cells.
3/ In the study, researchers tried to isolate INFECTIOUS #coronaviruses from samples taken from 108 people who retested positive. All of those samples tested negative.

Nearly all of them had neutralizing antibodies that prevent reinfection in at least the short term.💪
Read 4 tweets
When I started working on #scabies outbreaks in #carehomes some of my colleagues thought it was a weird, marginal interest. Now with #COVID19 it's changing. Everyone's realising that infection is a big deal in these #EndOfLife settings. Image
#Carehomes for older people are hard to study. Residents often have #dementia, staff are run off their feet, #consent to research is difficult - brilliant colleagues including @MedVetAcarology sorted this academic.oup.com/phe/article-ab…
Life expectancy on entry to a #carehome for older people is typically 8 months - these settings are largely #LastHomes. Everyone needs a plan for what will and won't happen for the common things likely to make them ill or deteriorate. #CPR probably not part of it
Read 13 tweets
How does the #pandemic end & how do we prevent a deadly resurgence of #Covid_19 later in the year? Release young people back into society first, a new paper says...
Bad situations occur if there is too little #socialdistancing (upper panel) or too much, causing a second wave of deaths (lower, an extreme case). Total mortality = TM; Green curves = #infections; blue = #ICU cases...
Here’s what happens if you release under 39 year-olds first. Here, either 2/3rds are released (assuming 1/3 live with older relatives; upper panels) or ALL of them are let out (lower panels). Total deaths drop from 1.5M to 900K to 390K...
Read 7 tweets
Lessons from past #coronavirus & #influenza #epidemics suggest that #viral #infections can trigger acute coronary syndromes, arrhythmias, exacerbation of heart failure owing to a combination of a significant systemic inflammatory response plus localized vascular inflammation.
#COVID19 may either induce new cardiac pathologies &/or exacerbate underlying cardiovascular diseases. A large proportion of patients have underlying cardiovascular disease &/or cardiac risk factors. Factors associated with mortality include male sex, advanced age, comorbidities.
Acute cardiac injury determined by elevated high-sensitivity #troponin levels is commonly observed in severe #COVID19 cases & strongly associated with mortality. Acute respiratory distress syndrome is also strongly associated with mortality in patients with #SARSCoV2 infection
Read 6 tweets
@jenbrea Hey! Yes several people spoke on that topic at the recent #ILADs conference I was at 👉 and remember this case history which found that a woman treated w/ antibiotics to target persistent #Bartonella had substantial improvement in EDS symptoms: ncbi.nlm.nih.gov/pmc/articles/P…
@jenbrea 2/2 As for #mast cell activation in response to persistent #pathogens...there is extensive literature on how a range of bacterial, viral and fungal pathogens can drive #MCAS-like symptoms 👉 for example: ncbi.nlm.nih.gov/pmc/articles/P…
@jenbrea 3/3 There is even a receptor common in #connective tissue who’s activity controls mast cell activation in response to bacterial signaling molecules that drive #biofilm formation: ncbi.nlm.nih.gov/m/pubmed/31278…
Read 11 tweets
Wow! 👉 This team found that 84% of patients w/ acute ischemic #stroke had bacterial DNA in their blood clots removed from the #brain ☝️oral #pathogen viridans streptococci (already connected to #endocarditis) was the most common organism identified in the #blood clots
Here is the paper itself which states 👉 “We found DNA of viridans streptococci in most aspired thrombi of patients with acute ischemic #stroke, which suggests that oral bacteria may have a role in the cause of #cerebrovascular disease.”
Also 👉 “Repeated transient bacteremia, caused by poor dental care or bacterial #infections, may trap pathogens in atherosclerotic plaques and promote rupture of the plaques”: ahajournals.org/doi/10.1161/JA…
Read 3 tweets

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