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Proud to present BA.5-infection risk drops after BA.1/BA.2 infection – data from the national Portuguese registry, one of the countries first hit with BA.5. Important, as adapted vaccines in development are BA.1-based. Follow the twitorial! 1/9 @lgraca medrxiv.org/content/10.110…
First, we used the SARS-CoV-2 genetic diversity surveillance data (great work from @irj_pt and J.P. Gomes) to define periods where each variant was dominant (>90% of national sample isolates). 2/9 #COVID19PT #DGS #INSA #InstitutoRicardoJorge 
Next, we extracted from the Portuguese COVID-19 registry (SINAVE) all infections from periods of dominance by each variant. SINAVE is very comprehensive, and until recently, there was a large testing effort in the country. Kudos to @DGSaude for maintaining the registry. 3/9
