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Opinion: vancomycin + cefepime + metronidazole (VCM) is superior empiric therapy than vancomycin + piperacillin/tazobactam (VPT) for *most* indications in the emergency department.
There are five reasons why I believe this to be true. #inthisessayiwill
There are five reasons why I believe this to be true. #inthisessayiwill
Empiric regimen selection for patients with healthcare-associated risk factors is tough.
Despite my bias, I hope to generate more thought in your next decision rather than simply saying....
Despite my bias, I hope to generate more thought in your next decision rather than simply saying....
1️⃣ VCM is more thoughtful than VPT.
Need anaerobic coverage? Add it! If you don’t, you’re not stuck with broader than necessary therapy.
Don’t need PsAr coverage? Drop to ceftriaxone.
VCM also allows for easier tailoring of therapy later during admission.
Need anaerobic coverage? Add it! If you don’t, you’re not stuck with broader than necessary therapy.
Don’t need PsAr coverage? Drop to ceftriaxone.
VCM also allows for easier tailoring of therapy later during admission.
