Discover and read the best of Twitter Threads about #ionchannels

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Open water swimmers and winter people all, do you wonder how you feel cold? Well it’s the wonder of nerves again - let me tell you some nerve nerdy stuff... #openwaterswimming #thestoics #sensorynerve #cold
A thread :
Cool is a pleasurable feeling and warm too but hot and cold break into painful feelings. This appreciation of temperature is a protective function of nerves but how does it all work? How does your body tell your brain about the word outside?
If we step into a lake or river in winter the free nerve endings in the skin can tell us what temperature the water is. This is possible between -10 and 60°C in mammals. How this works is a very clever story and is linked with 🌶 and mints! Keep reading.. 🧊
Read 16 tweets
Buenos días! Ahora estaré a cargo yo @Kimgmz6 de la cuenta!
En nuestro laboratorio tratamosde comprender cómo los canales iónicos, específicamente los canales de calcio y sodio dependientes de voltaje, están regulados durante el dolor!
Los canales iónicos son proteínas oligoméricas que están ancladas en la membrana plasmática de las neuronas. Estos responden a los cambios en la diferencia de cargas eléctricas en ambos lados de la membrana y permiten que los iones como calcio o sodio pasen a través del canal.
La actividad de estos canales es requerida para muchas funciones fisiológicas, sin embargo, en algunas patologías su función está alterada.
Durante el dolor, se ha visto que la expresión y/o actividad de algunos subtipos de estos canales está aumentada.
Read 6 tweets

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