Discover and read the best of Twitter Threads about #isc
Most recents (7)
More or less a year ago the #IOTA Foundation announced two new networks.
#Shimmer a staging network and #Assembly a permissionless Layer2 network building on top of #IOTA.
Let's put together everything we know and speculate about their adoption and price.
A👇🧵
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#Shimmer a staging network and #Assembly a permissionless Layer2 network building on top of #IOTA.
Let's put together everything we know and speculate about their adoption and price.
A👇🧵
1/44
Okay so first we need to get a little bit of an overview of everything #IOTA.
We need to separate between networks and technology upgrades. This is necessary to keep a clear picture of everything we will talk about in this Thread
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We need to separate between networks and technology upgrades. This is necessary to keep a clear picture of everything we will talk about in this Thread
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@OscarOrue @Tributacionpy #IVA "El tema de la deducibilidad del IVA es una ley sancionada y nosotros estamos trabajando sobre la posibilidad del veto. Es una norma constitucional y rompe con el principio de igualdad", viceministro @OscarOrue, @Tributacionpy. #730AM
@OscarOrue @Tributacionpy #IVA "No estamos analizando el tema del combustible dentro del IVA. No estamos analizando que eso se cambie", viceministro @OscarOrue, @Tributacionpy. #730AM
#WeekendLecture
#Tenecteplase #TNK
Part 1
✅3rd generation rtPA
🧬Targeted genetic upgrade
3 specific alterations to #alteplase molecule:
👉⬆️Half life
👉⬆️Binding affinity for #fibrin
👉⬆️Resistance to inactivation by #PAI-1
bit.ly/3pqbEb1
#Tenecteplase #TNK
Part 1
✅3rd generation rtPA
🧬Targeted genetic upgrade
3 specific alterations to #alteplase molecule:
👉⬆️Half life
👉⬆️Binding affinity for #fibrin
👉⬆️Resistance to inactivation by #PAI-1
bit.ly/3pqbEb1
#WeekendLecture
#TNK
👉⬆️T1/2 allows single bolus dosing and⬆️clot exposure to TNK
👉Higher affinity to fibrin-rich clots & + potent/faster clot #lysis vs alteplase
👉 < consumption of fibrinogen/plasminogen/ a2- antiplasmin👉⬇️systemic fibrinolytic effect👉⏬risk for bleeding
#TNK
👉⬆️T1/2 allows single bolus dosing and⬆️clot exposure to TNK
👉Higher affinity to fibrin-rich clots & + potent/faster clot #lysis vs alteplase
👉 < consumption of fibrinogen/plasminogen/ a2- antiplasmin👉⬇️systemic fibrinolytic effect👉⏬risk for bleeding
#WeekendLecture
#TNK
First analysis in stroke patients was a #dose-scalation safety study
There was no #symptomatic ICHs in dosis of 0.1-0.2-0.4mg/kg, and 15% (2 of 13) in 0.5mg/kg
No differences in clinical outcomes
bit.ly/3DNHamV
#TNK
First analysis in stroke patients was a #dose-scalation safety study
There was no #symptomatic ICHs in dosis of 0.1-0.2-0.4mg/kg, and 15% (2 of 13) in 0.5mg/kg
No differences in clinical outcomes
bit.ly/3DNHamV
#ACHEST in partnership with @MinofHealthUG and @ngoradlg3 are implementing a project on Intersectoral Collaboration (ISC) for #PrimaryHealthCare
Read more 👉achest.org/index.php?opti…
Read more 👉achest.org/index.php?opti…
The project is premised on the principle that good health starts with, and is created by individuals, their families and the communities; and that individuals have the primary responsibility for maintaining their own health. achest.org/index.php?opti…
Village Health teams(VHTs) maintain registers with records of the health status of each individual in the households; and promote and record good health practices, hygiene and health conditions of household members.
Nice. The #ISC has finally published the #RussiaReport... on @Google docs:
docs.google.com/a/independent.…
docs.google.com/a/independent.…
Exclusive: MPs who drew up the #Russia report were told the #Kremlin has a "likely hold" over Donald #Trump and there were "indications" #Moscow interfered in and may have covertly funded the 2016 #Brexit vote - my new book Shadow State reveals theguardian.com/world/2020/jun…
The evidence - given by former MI6 officer Christopher Steele - is the most compelling explanation so far as to why Boris #Johnson still refuses to publish the missing #Russia report, which he suppressed before last December's UK general election
In a confidential 2018 memo to the British parliament's intelligence and security committee (ISC) Steele accuses Theresa May and Johnson - at that point foreign secretary - of putting "party political interests" above "national security" - a "serious mistake", in his view
And here we are...
#10yearsofTESD in #TESDquotes!
Happy birthday and 10 years #TellEmSteveDave!!!
¡Feliz cumpleaños!
[opens thread] 👇🏻🐜🎧💜🎉
#TESD #TESDlove #TESDTEN
#10yearsofTESD in #TESDquotes!
Happy birthday and 10 years #TellEmSteveDave!!!
¡Feliz cumpleaños!
[opens thread] 👇🏻🐜🎧💜🎉
#TESD #TESDlove #TESDTEN
Walt (about the podcast) "Once it became important to you, it became important to me."
Bry "Oh, you're so full of shit!"
#TESD1
Bry "Oh, you're so full of shit!"
#TESD1
Walt to Bry "We can close the show with a little Steve-Dave rant."
#TESD2
#TESD2
