Discover and read the best of Twitter Threads about #isth2022

Most recents (3)

Perioperative #DOAC management. Important differences between PAUSE and ASRA. How can we come to consensus? Dr Douketis is proposing PAUSE-2 trial aiming for a single approach. #ISTH2022 ImageImageImage
He performed a small, pilot study to assess feasibility of randomizing to ASRA vs PAUSE approach. High level of consent in this cohort. Will other sites be willing to randomize? I hope so! #ISTH2022 ImageImageImageImage
Interestingly, both approaches had similarly low #DOAC drug levels. How well protocols were followed and impact of renal function will be important to explore. #ISTH2022 Image
Read 3 tweets
Thrombin generation assays doing a lot of work at non factor therapy for #hemophilia session at #Isth2022 demonstrating

1/4 🧵

1️⃣ Stability of antithrombin knockdown in subjects receiving fitusiran Image
2️⃣ Increased potency of Mim8 compared to emicizumab in phase 1 subjects Image
3️⃣ Potential use of emicizumab in select #hemophilia B patients Image
Read 4 tweets
SOA live: Dr Zoe McQuiltern on TXA for major bleeding. Surgery/trauma acct for majority of MB but I note worse survival for GIB
#ISTH2022 prehospital STAMP confirms effect size of TXA in trauma from CRASH2 but underpowered. Exploratory analysis suggests Earlier admin within 1h, better outcomes
#ISTH2022 prehospital STAMP confirms effect size of TXA in trauma from CRASH2 but underpowered. Exploratory analysis suggests Earlier admin within 1h, better outcomes
Read 9 tweets

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