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Tweetorial 1 / Eficacia de la vacuna #HPV de @RecheckHealth

¿Te importaría empezar el año nuevo con un TWEETORIAL? Nuestro humilde homenaje a-@VPrasadMDMPH te guiará a través de la evidencia sobre las vacunas #HPV y lo que @Cochranecollab hizo de ella.
2/n Primero acordemos una cosa: los ensayos controlados aleatorios (ECA) son superiores a los estudios observacionales @JuanGrvas @RedeSciELO
3/n En las vacunas contra el VPH, muchos estudios observacionales publicados y los ensayos controlados aleatorios promocionados de #Gardasil #Cervarix no pudieron demostrar la eficacia esperada sin embargo. Es triste, verdadero y poco discutido. Echemos un vistazo más de cerca
Read 26 tweets
Care to kick off the New Year with a TWEETORIAL? Our humble homage to @VPrasadMDMPH will walk you through the evidence on #HPV vaccines and what @Cochranecollab made of it. Let’s first agree on one thing: RCTs are superior to observational studies
On HPV vaccines many observational studies published and hyped Randomized Controlled Trials on #Gardasil #Cervarix failed to demonstrate the expected efficacy though. It is sad, true and rarely discussed. Let’s have a closer look. @garyschwitzer @HealthNewsRevu @senseaboutsci
In 2006 @US_FDA VRBPAC Committee required @Merck to provide data and analyses on Gardasil RCTs FUTURE I and II.
Which outcome would you consider as the most relevant to assess Gardasil efficacy?
Read 22 tweets

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