Discover and read the best of Twitter Threads about #kefir

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Our recent work uses #kefir – a natural milk fermenting community – to unravel mechanisms of coexistence in complex communities. Now on bioRxiv: biorxiv.org/content/10.110… (thread 1/5)
We show how microbes poorly suited for milk surprisingly dominate the kefir community through metabolic cooperation. The kefir grain acts as a ‘basecamp’ for this complex community (30-50 species), from which they colonize the milk in a complex yet organized manner (thread 2/5)
The ability of the microbial species in kefir to stick together and collaborate is what makes them successful, e.g. by being more stress resistant. This image shows one of the interaction networks we uncovered for kefir species
(thread 3/5)
Read 5 tweets
Round 2 of the Great ID Debates of #ASHP18 @ASHPOfficial comes to us from the brilliant minds of @SIDPharm members @TimbrookTT and @julie_justo. To start us off, Tristan makes the case for #fidaxomicin (FID) for treatment of Clostridioides difficile (#cdiff) infection
.@TimbrookTT sets up the major points for FID in the treatment of #Cdiff: 1- ⬇️recurrence compared to #vancomycin (VAN) in RCTs + ⬆️in cure without recurrence (aka global clinical cure) 2- this held up in real-world data 3- cost-effectiveness analyses support 1st line use #ASHP18
.@TimbrookTT notes the 2018 @IDSAInfo guidelines for #cdiff (idsociety.org/practice-guide…) recommend FID equally to VAN and for first recurrence, quality of evidence is higher 👀🤔#ASHP18
Read 23 tweets

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