Discover and read the best of Twitter Threads about #lanadelumab

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Aleena Banerji, MD
@AleenaBanerjiMD
1/ New guidelines from the @US_HAEA Advisory Board are now available @JACIInPractice. We provide an update on classification, diagnosis, on-demand/prophylactic tx with special considerations for women/children along with guidance on development of a comprehensive management plan.
2/#HAE can be broadly divided into #HAE due to C1INH deficiency (type 1 and type 2) and HAE with normal labs (4 mutations now identified - factor XII, plasminogen,
angiopoetin-1, and kininogen). Early diagnosis is critical. If you suspect send C4, C1INH level and function.
3/All patients with #HAE must have ready access to effective on-demand medication and trained in self-administration. Encourage on-demand treatment of all #HAE attacks. Four FDA approved on-demand treatments available (ecallantide, icatibant, pdC1INH, or rhC1INH)
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#HAE #kallikrein #berotralstat #lanadelumab

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