Discover and read the best of Twitter Threads about #métastases

Most recents (3)

🧐#TribuneScientifique sur les RÉACTIVATIONS DE CANCER POST-VAX

Selon Pr.#AngusDalgleish oncologue @StGeorgesUni ces observations "doivent être diffusées & débattues IMMÉDIATEMENT"

"LE LIEN DU VACCIN AVEC LES CAILLOTS/
MYOCARDITE/CRISES CARDIAQUES/AVC EST maintenant BIEN ÉTABLI
Tout comme le lien avec la MYÉLITE et la NEUROPATHIE!"

Cependant: "il existe maintenant une autre raison d'arrêter tous les programmes de vaccination. En tant qu'oncologue praticien, je vois des personnes atteintes d'un cancer stable progresser rapidement après un rappel..."
"Je suis suffisamment expérimenté pour savoir que ce ne sont pas les anecdotes fortuites que beaucoup suggèrent, d'autant ➕ que le même schéma est observé
-en #Allemagne
-en #Australie
-aux #USA"
Read 6 tweets
Major update for small cell #lung cancer! #LCSM

With @juliensage + @FoundationATCG, our paper now on @bioRxiv:

►Genomic analysis of *3,600* pts with SCLC; largest SCLC study to date!

►Multiple interesting findings discussed in this 🧵
biorxiv.org/content/10.110…
🧵2
This study is unique in many ways:

> The #SCLC cohort studied came mostly from community sites --> representing a more typical “real-world” cohort of SCLC.
> The genomic data are tied to clinical data + outcomes.

#LCSM
🧵3
To the best of our knowledge, our study analyzes the largest number of SCLC tumors from African ancestry to date:
> n=256 AFR cases
> 7.1% of the entire cohort
#Diversity in clinical studies is critical!!
See tweet 🧵9 for more details.
Read 15 tweets
Very happy to see our microRNA metastases paper out. co-led by @HyeEirik and by many fantastic colleagues

We show the reasons for previously published contradicting reports of de-regulated #microRNAs in colorectal cancer #tumors and #metastases:

tinyurl.com/yckwdk2z
Among them are
- lack of correction for background expression
- different metastatic sites were not analyzed as separate entities
- expression cut-off level for microRNAs to ensure biological relevance are typically not used
We establish a stringent, reproducible and easily expandable bioinformatics pipeline (github.com/eirikhoye/mirn…) that we applied on all previously published (depending on availability) and a large range of novel smallRNA sequencing datasets, altogether 268 datasets.
Read 11 tweets

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