Discover and read the best of Twitter Threads about #m1Ψ

Most recents (2)

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If this show is done and people realized who treated them, you're done, too. This is not a threat but a sober statement.

You clowns don't have science. Just claims: the full paper shit show. (We can't do this often enough.)
2/

Each single word clowns like @TheDrJon are parotting - like it is the bible - is unscientific bullshit.

1st remember the modified 12s 3'UTR (mtRNR1) and how they messed: #m1Ψ

cell.com/molecular-ther…

web.archive.org/web/2022090308… ImageImageImage
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ncbi.nlm.nih.gov/pmc/articles/P…

How many m1Ψ has a normal human mRNA-strand? How many a RNA-Virus?! So no messenger RNA! ImageImage
Read 21 tweets
Developing an #mRNA vaccine is a sure-shot way to success? No! Despite the spectacular performance of #Pfizer & #Moderna vaccines, we also have a #CureVac fiasco. We need to dig in much deeper into the intricacies of developing a highly efficacious mRNA vaccine 1/
There is more than low dose & impact of VOCs behind #CureVac’s failure. And here we once again need to salute the sheer brilliance of @kkariko . Will do a little thread to explain, why! 2/
No doubt, the #CureVac used a much lower #RNA dose. Dose is lower (12 (CureVac) vs 30 (#Pfizer) vs 100 ug (#Moderna)) but no idea how that translates to protein. Need to know how much of a role the lower dose played in the lower efficacy 3/
Read 20 tweets

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