Discover and read the best of Twitter Threads about #malignancies
Most recents (2)
@MondayNightIBD 2/📣#IBD & meds carry an⬆️risk of #Malignancies, including lymphomas
🔺Who is at risk?
🔺Is it IBD-mediated or drug-related?
🔺What is our prevention & screening🔎strategy?
Thank you for joining this special #MondayNightIBD #Back2Basics @DuekerJeffrey
🔺Who is at risk?
🔺Is it IBD-mediated or drug-related?
🔺What is our prevention & screening🔎strategy?
Thank you for joining this special #MondayNightIBD #Back2Basics @DuekerJeffrey
@MondayNightIBD @DuekerJeffrey @amelia_kellar @DCharabaty @IBD_Afzali @drdani23 @ibddoctor @EdithHoMD @fgomollon @IBD_DrEMF @ibdgijami @MaiaKayalMD 3/ 🔥IBD may carry a unique risk of primary intestinal lymphoma (PILD), but NO🔼risk of extra-intestinal NHL
In CESAME population,
▪️Crude IR of PILD was 0.12/1000 patient-years (py)
▪️All B-cell NH LD
▪️79% ♂️, 11 CD, 3 UC
▪️86% arose in IBD lesions
▪️45% were EBV positive
In CESAME population,
▪️Crude IR of PILD was 0.12/1000 patient-years (py)
▪️All B-cell NH LD
▪️79% ♂️, 11 CD, 3 UC
▪️86% arose in IBD lesions
▪️45% were EBV positive
@MondayNightIBD @DuekerJeffrey @amelia_kellar @DCharabaty @IBD_Afzali @drdani23 @ibddoctor @EdithHoMD @fgomollon @IBD_DrEMF @ibdgijami @MaiaKayalMD @JChristieMD @KDeFelice_IBD @dunleavy_katie @IBDMD @MN_GIMD @SaraElOualiMD @nloganmd @KrugCleveland @PDulaiMD @PriSantiagoMD 4/ Lymphoma in #IBD is mostly linked to IBD therapy, particularly #Thiopurines (6MP, AZA)
🔺⬆️Risk in CD, less evidence with UC
🔺M>F
🔺Risk increases with exposure⏲️, particularly >2 years
🔺Risk decrease after cessation of AZA
🔺⬆️Risk in CD, less evidence with UC
🔺M>F
🔺Risk increases with exposure⏲️, particularly >2 years
🔺Risk decrease after cessation of AZA
1/
#Cryptococcal Infection in #Hematologic #Malignancies and Hematopoietic Stem Cell Transplantation
Here we review crypto with attention to its background, epi, risk factors, presentations, diagnosis, treatment, & prevention in hematologic malignancies
pubmed.ncbi.nlm.nih.gov/32740974/
#Cryptococcal Infection in #Hematologic #Malignancies and Hematopoietic Stem Cell Transplantation
Here we review crypto with attention to its background, epi, risk factors, presentations, diagnosis, treatment, & prevention in hematologic malignancies
pubmed.ncbi.nlm.nih.gov/32740974/
2/
At baseline, even prior to the start of immunosuppression, newly diagnosed patients with heme malignancies have cellular & humoral immune deficits with functional and absolute defects in granulocyte and lymphocyte function
that place patients at increased risk for infections
At baseline, even prior to the start of immunosuppression, newly diagnosed patients with heme malignancies have cellular & humoral immune deficits with functional and absolute defects in granulocyte and lymphocyte function
that place patients at increased risk for infections
3/
Below is how crypto comes in from the environment. Note the very cool "Trojan horse" mechanism to get into the CNS!
Below is how crypto comes in from the environment. Note the very cool "Trojan horse" mechanism to get into the CNS!
