Discover and read the best of Twitter Threads about #membereducation
Most recents (5)
1/ Want to continue the learning streak of #Kidneywk ?
#MedTwitter #NephTwitter, we bring another #ASPNFOAM group tweetorial based on pathology webinar @ASPNeph on T-cell mediated rejection(TCMR) in kidney transplant (Tx)
#MedTwitter #NephTwitter, we bring another #ASPNFOAM group tweetorial based on pathology webinar @ASPNeph on T-cell mediated rejection(TCMR) in kidney transplant (Tx)
2/
Let's start with a vignette! 13 yr M with CAKUT s/p DDKT 6mo ago, p/w with doubling of Cr from 0.7 to 1.5 mg/dl, normal vitals and PE. UA normal. A lot of recent stressors and concern for non-adherence.
Sounds like a familiar scenario?
Let's start with a vignette! 13 yr M with CAKUT s/p DDKT 6mo ago, p/w with doubling of Cr from 0.7 to 1.5 mg/dl, normal vitals and PE. UA normal. A lot of recent stressors and concern for non-adherence.
Sounds like a familiar scenario?
What is the potential cause of graft dysfunction in this patient?
1/This July’s @aspneph pathology webinar was all about pediatric Antineutrophil Cytoplasmic Antibody (ANCA)- associated vasculitis (AAV). Let's kick off this pediatric AAV tweetorial✍️with a quick question #NephTwitter
🤔 What is the role of ANCA antibodies❓
🤔 What is the role of ANCA antibodies❓
2/
✅Diagnostic marker and Pathogenic in nature
▶️ Proteinase-3 (PR3) and Myeloperoxidase (MPO) antigens are sequestered in neutrophil primary granules
▶️ Antigen exposure triggers immune response leading to endothelial activation
linkinghub.elsevier.com/retrieve/pii/S…
✅Diagnostic marker and Pathogenic in nature
▶️ Proteinase-3 (PR3) and Myeloperoxidase (MPO) antigens are sequestered in neutrophil primary granules
▶️ Antigen exposure triggers immune response leading to endothelial activation
linkinghub.elsevier.com/retrieve/pii/S…
3/
Mechanisms
📌Defective neutrophil apoptosis, leading to NETosis
📌Inefficient clearance of PR3/MPO
📌Antimicrobial antibodies cross reacting with PR3/MPO
📌Medication induced
Mechanisms
📌Defective neutrophil apoptosis, leading to NETosis
📌Inefficient clearance of PR3/MPO
📌Antimicrobial antibodies cross reacting with PR3/MPO
📌Medication induced
1/ Hi #NephTwitter #Renal #MedTwitter @ASPNeph radiology webinar this month was Vesicoureteral reflux #VUR and its management.
Let's get going with a poll!
What percentage of children with febrile UTI may end up having VUR?
Let's get going with a poll!
What percentage of children with febrile UTI may end up having VUR?
2/ Answer: up to 30%
This may be an underestimate since many children don't get tested.
[PMID: 9743033] pubmed.ncbi.nlm.nih.gov/9743033/
This may be an underestimate since many children don't get tested.
[PMID: 9743033] pubmed.ncbi.nlm.nih.gov/9743033/
3/ Risk factors for VUR:
⚡️Bowel and bladder dysfunction
⚡️Abnormal urinary tract anatomy
⚡️Younger children and infants
⚡️Girls affected >> boys
⚡️Family history: sibling with VUR ➡️ 25% recurrence risk
Read more 👇
PMID: pubmed.ncbi.nlm.nih.gov/33869117
⚡️Bowel and bladder dysfunction
⚡️Abnormal urinary tract anatomy
⚡️Younger children and infants
⚡️Girls affected >> boys
⚡️Family history: sibling with VUR ➡️ 25% recurrence risk
Read more 👇
PMID: pubmed.ncbi.nlm.nih.gov/33869117
1/📢Hello #medtwitter
This month's (Aug) @ASPNeph Radiology webinar was all about vesicoureteral reflux (VUR)
Here are some clinical pearls!
What's new!?
#Medtweetorial #nephtwitter #ASPNeph #vesicoureteralreflux #vur
VUR - Against the flow!
This month's (Aug) @ASPNeph Radiology webinar was all about vesicoureteral reflux (VUR)
Here are some clinical pearls!
What's new!?
#Medtweetorial #nephtwitter #ASPNeph #vesicoureteralreflux #vur
VUR - Against the flow!
2/ Let's get started with a poll!
Which one of these is true about VUR?
Which one of these is true about VUR?
3/ Ans - All the above
PMID: 32022517
Let's quickly define vesicoureteral reflux
Retrograde flow of urine from the bladder into the upper urinary tract due to dysfunctional vesicoureteric junction (VUJ)
PMID: 32022517
Let's quickly define vesicoureteral reflux
Retrograde flow of urine from the bladder into the upper urinary tract due to dysfunctional vesicoureteric junction (VUJ)
1/
📢Hello #MedTwitter.
This month’s @ASPNeph Renal Pathology webinar is all about #IgAVasculitis #IgAVN formerly known as #HSP.
Urine for a treat!
#nephtwitter
Let’s do a quick poll! Iga Vasculitis is most common in which age group?
📢Hello #MedTwitter.
This month’s @ASPNeph Renal Pathology webinar is all about #IgAVasculitis #IgAVN formerly known as #HSP.
Urine for a treat!
#nephtwitter
Let’s do a quick poll! Iga Vasculitis is most common in which age group?
2/
A: <10 years, about 90% of cases of IgA Vasculitis are seen in children under 10
🤯
A: <10 years, about 90% of cases of IgA Vasculitis are seen in children under 10
🤯
3/
Let's talk numbers-
1⃣Kidney involvement in 30-50%
2⃣Kidney involvement appears within 6 weeks in 91%
3⃣IgA Vasculitis preceded by URI in 50%
4⃣If nephro findings, 10% progress to ESRD/severe CKD in 10 years
PMID: 139081 PMID: 32356414 PMID: 32060820
Let's talk numbers-
1⃣Kidney involvement in 30-50%
2⃣Kidney involvement appears within 6 weeks in 91%
3⃣IgA Vasculitis preceded by URI in 50%
4⃣If nephro findings, 10% progress to ESRD/severe CKD in 10 years
PMID: 139081 PMID: 32356414 PMID: 32060820
