Discover and read the best of Twitter Threads about #mesospim

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The CompassLSM: an #opensource #mesoSPIM-inspired #lightsheet #Microscope excitation path that allows 3.5 um axial resolution over a 10 mm FOV using axially scanned lightsheet microscopy osapublishing.org/boe/fulltext.c…
My main comment about this paper is about publication strategy and not science: I probably should not have called it #opensource: "CAD file available upon request" - it should be easier than that! Don't make it so hard for biologists to copy your work!
If you want your technology adopted, make adoption really, really easy - find a vendor for parts kits, provide the complete parts list, provide software, provide documentation - don't let users do a lot of the legwork. Lowering the barrier to entry is key.
Read 8 tweets
We are excited to share the mesoSPIM, a versatile open-source light-sheet microscope for imaging in cleared tissue. #mesoSPIM @openSPIM #lightsheet
Check out our webpage: mesospim.org
The mesoSPIM is compatible with all clearing techniques and was tested with
active and passive CLARITY, CUBIC, BABB, iDISCO and MASH.
The key mesoSPIM feature is axially scanned light-sheet microscopy (ASLM) introduced by @RetoPaul and @kD3AN which allows uniform axial resolution across large FOVs. To translate the light-sheet, we are using tunable lenses from
@optotunecompany
Read 14 tweets

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