Discover and read the best of Twitter Threads about #metabolomics

Most recents (6)

🧵🧵 THREAD: #Bioinformatics applications - a deep dive into #pipelines and #workflows 🧵🧵
1. #Bioinformatics is the application of #computational techniques to the #analysis of #biological #data, such as #sequences, #structures, and #interactions, and is an essential field of modern biology and medicine.
2. #Bioinformatics has many exciting applications in various fields, such as #genetics, #genomics, #proteomics, and #metabolomics, that can provide new insights into the workings of living systems, and can help to advance science and society.
Read 8 tweets
Now we'll talk #polyphenols and #PrecisionNutrition in this next science packed session at #Nutrition2022. #NutritionLiveOnline Image
Oh look the #microbiome is here too! 🥰👏🥳 Yes, polyphenols are key to the #GutMicrobiome. Let's learn more.
#Nutrition2022 #NutritionLiveOnline Image
But first the #metabolome and polyphenols. #Nutrition2022 #NutritionLiveOnline Image
Read 12 tweets
I told my family from age 7 that I wanted to be a zoologist.

I am so proud of myself for all I have achieved so far and am grateful for life's opportunities everyday.

Our STEM journeys are important and I am excited to share mine with you.
I graduated in BSc (hons) Zoology from @AngliaRuskin in 2015.

I struggled, mostly with exams.

After three years, I convinced myself I would never be smart enough to pursue any post-graduate studies so I got a job at @sangerinstitute as an animal tech 🐭
I immediately fell back in love with science.

I realised that commitment and enthusiasm were just as valuable as being able to take an exam.

I learnt so much from so many and before I knew it, I was looking up papers in the evening just to better contribute to the conversations
Read 11 tweets
Multi-Omic inTegrative Analysis (MOTA): an application of differential network analysis to #multiomics.

✓3 non-TCGA datasets (HCC vs CIRR)
✓explanations for parameters & rgCCA choice
✓good at known cancer drivers recovery
✓consistent across cohorts

#SundayMultiOmics 1/n
[[ Detailed description & comments follow ]]
Figures © by authors, reused under CC-BY 4.0…
Developed @LombardiCancer @gumedcenter (sorry I could not to find authors on Twitter)
["Layman" introduction]: many studies focus on the differences in the abundance of specific biomolecules; while very useful to highlight the obvious #biomarkers, it may not explain complex disease mechanisms & can be very sensitive to cohort differences (e.g. in #metabolomics)
Read 17 tweets
Published open access version of our workflow for non-targeted LC-MS #metabolomics is now available in @MDPIOpenAccess Metabolites! This is huge work, and I'll be breaking down some of the main parts in following tweets.👇
The paper includes full lab protocol for performing non-targeted LC-MS #metabolomics.
There is also a description of the full #bioinformatics analysis pipeline, from preprocessing to statistics, classification, visualization and so on.
Read 6 tweets
This is pretty wild, looking at the paper now, but they took gut bacteria from (human) schizophrenic folks and non-schizophrenic controls and put it into germ free mice. The mice with the scz bacteria had changes in behavior and CHANGES in the glutamate modulation in the brain.
H/T @mostrolenk here is a write up of the findings...…
Read 10 tweets

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