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Are there individual differences in response to antipsychotic treatment?

Excited to share our new paper, now online @JAMAPsych. Here's an overview of what we did and what we found.
So what's the problem here? Isn't it obvious that patients respond very differently to treatment? After all, that's why everyone talks about personalizing medicine, right? Well, not so fast. It turns out that things are actually less clear: nature.com/articles/d4158…
Statisticians such as @stephensenn @statsepi @f2harrell and others have repeatedly pointed out that the typical responder analysis of RCT data is quite problematic: darrendahly.github.io/post/2017-08-1…
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