Discover and read the best of Twitter Threads about #monoclonalantibody

Most recents (8)

I am so sick and tired of #CaseyDeathSantis telling me “who her husband is”. The melodrama is intense. He’s the man who wouldn’t mask in public when you were ill, Casey. He’s the man who hid tens of thousands of Deaths. He’s the man who profited from antibody treatments. Oh, wait
Weren’t the shares in the Antibody Treatment Maker in Casey’s name? The couple who #grifts together, campaigns together. Same with the scam of a disaster relief fund she fronts. #scammer #grifter
Ok. I have to say that the shares were “allegedly” in Casey’s name. I can’t find the story now, but way back when #DeathSantis made it hard to get vaccines but was doling out #MonoclonalAntibody treatments at state expense. The story was that Casey owned stock, but lost money…
Read 4 tweets
#EUCommission to buy over 200,000 COVID anti-body treatments | 15:52
- #Sotrovimab, developed by #GlaxoSmithKline in collaboration with VIR biotechnology, is part of the first portfolio of five COVID-19 therapeutics announced by the Commission in June 2021
euractiv.com/section/corona…
Covid-19: Patients vouch for effectiveness of #Sotrovimab | Jul 24
- Patients treated with Sotrovimab, the new #Covid19medicine, praised the effectiveness of the drug to reduce symptoms in a matter of days.
khaleejtimes.com/coronavirus-pa…
#Sotrovimab is an investigational human neutralizing dual-action #monoclonalantibody with activity against severe acute respiratory syndrome coronavirus 2, known as #SARSCoV2.
- Sotrovimab is designed to attach to the spike protein of SARS-CoV-2.
en.wikipedia.org/wiki/Sotrovimab Image
Read 4 tweets
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses. Image
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011 Image
The influence of #HLA genotype on the severity of #COVID19 infection
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic. Image
Read 199 tweets
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action. jjcouey.medium.com/5-concerns-abo…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus. Image
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component. Image
Read 213 tweets
Reducing #COVID19 #Airborne #Transmission Risks on #PublicTransportation Buses
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%. Image
🔝#SARSCoV2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies. Image
High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others Image
Read 236 tweets
⚠️#Ocular #MRI Findings in Patients with Severe #COVID19: A Retrospective Multicenter Observational Study
» doi.org/10.1148/radiol…
All patients had nodules in the macular region, 8/9 (89%) had bilateral nodules, 2/9 (22%) had nodules outside the macular region. Screening needed. Image
⚠️🔝New-Onset #IgG #Autoantibodies in Hospitalized Patients with #COVID19
» doi.org/10.1101/2021.0…
An international team of researchers studying COVID-19 has made a startling and pivotal discovery: The virus appears to cause the body to make weapons to attack its own tissues. Image
⚠️🔝Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance
» academic.oup.com/eurheartj/adva…
Damage to the heart found in more than half of #COVID19 patients discharged from hospital who show raised levels of troponin. Image
Read 235 tweets
Monoclonal antibody

#RNA_Virus के विरुद्ध कितनी वैक्सीन बनी है?
वायरस में RNA होगा या DNA
विशुद्ध जेनेटिक मटीरियल तो DNA ही है, DNA से RNA बन जाता है और RNA से प्रोटीन! प्रोटीन ही सारी क्रिया और सरंचना में भागीदार है। यह सामान्य सा नहीं सभी पर लागू होता है।

1/N
कोई DNA वायरस हो तो हम वैक्सीन आसानी से बना लेते है।

जब बात RNA वायरस कि आती है तो यह उल्टा चलने लगता है। जैविक अणु विकास की यह विचित्र घटना है जब RNA वायरस हमारा पानी एंजाइम का उपयोग कर DNA भी बनाता है अपना विकास करता है। तो क्या हम अपने ही विरुद्ध वैक्सीन बना दे।

2/N
कोराना वायरस है तो RNA वायरस लेकिन इसके साथ एक कमजोरी है। जो इसकी संक्रामकता में छिपा है! इसके शरीर के बाहरी खोल पर छोटे छोटे उभार है जिन्हें हम spike कहते है! यह एक तरह का प्रोटीन! ग्लाइकोप्रोटीन है। ऐसे ही spike हमारे शरीर मे भी होते है जिससे यह वायरस चिपक रहा है।

3/N
Read 8 tweets
#HematologyTweetstory 21: the “CD” nomenclature. Musical CDs may be obsolete (though I still have a lot of them from college days; Paul Simon’s “Graceland” wins for most listens). Communicating clearly about blood cell surface markers? Here to stay.🙂 @ASH_Hematology #hemepath/1
In the 1970s, German Georges Köhler & Argentinian-born César Milstein at @MRC_LMB fused myeloma cell lines w/ B cells to create immortal “hybridomas” that could produce specific monoclonal antibodies. Development of MoAbs led to a wave of discovery of cell-identifying markers./2
In the late 1970s & early 1980s, labs all across the world used this new #monoclonalantibody technology to move beyond morphology in cell identification. The same cell surface molecule identified by multiple laboratories was given different names. It got hard to read papers!/3
Read 21 tweets

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