Discover and read the best of Twitter Threads about #mortality

Most recents (24)

"The metaverse... besides being immersive and interoperable, it's meta-physical, that is, a realized illusion, an impossibility in the round, able to absorb an infinite number of contradictions and convert them into fuel for growth."--Martin Gurri @mgurri greeneracresvaluenetwork.wordpress.com/2022/05/18/dai…
A fundamental limit to the search for the oldest fossils | Nature Ecology & Evolution
nature.com/articles/s4155…
#PaleontologicalResearch, #FossilAge, #LifeOrigins
Read 13 tweets
Exactly 7 years ago, I spent #StrokeAwarenessDay undergoing emergency #thrombectomy for #basilar artery occlusion. #BAO

Today, I'm still in awe and celebrating how #modern #medicine saved me from locked-in syndrome and enabled me to live a normal life, against all odds.

1/ 🧵
2/ So far, I have avoided sharing this information as part of my professional life, fearing it would somehow disqualify me as a credible clinician-scientist. Finally, I realize that the experience only strengthened my resolve to give future patients the second chance I was given.
3/ What happened in brief:

I was a healthy, 25yo medical student, all excited to have finished the first 10K run of my life not even 5 hours before my family reacted #FAST and called 911.
Read 20 tweets
9) Many risk factors modulate the propensity of LDL-C to traverse the endothelium and enter the arterial intima. See 🔓academic.oup.com/eurheartj/arti….
10) It now appears that the passage of #LDL into the #intima is not a merely passive process whereby the concentration in blood & the permeability of the endothelium determine LDL accumulation.
11) It’s #Transcytosis (an active process), through a vesicular pathway involving #caveolae, scavenger receptors (#SRB1) and activin like receptor kinase 1 (#ALK1). Hence for a given blood level of LDL-C the amount of atherosclerosis is variable.
Read 36 tweets
PLEASE do not use the @CDCgov data on deaths to compare #COVID19 #mortality per capita in #Florida to other states.

Below, I created a viz from the CDC COVID Tracker to compare 5 states. Florida is the green line and the red arrow shows a recent decrease.

1/5
Despite that suggested DECREASE in FL...

I just tweeted this out highlighting the recent INCREASE (almost a doubling) is reported COVID-19 deaths this week.



What gives?

2/5
The way in which states report mortality data to @CDCgov is not the same. Almost all report based on date reported.

FL reports by date of death

That is NOT a criticism - I like the way FL reports it so I can calc both types of curves - but it is a caution for comparison.

3/5
Read 5 tweets
Daily Bookmarks to GAVNet 12/15/2021 greeneracresvaluenetwork.wordpress.com/2021/12/15/dai…
Well-Structured German Study Shows No Deaths among Healthy German Kids Ages 5 to 11 ⋆ Brownstone Institute

brownstone.org/articles/well-…

#MedicalStudy, #germany, #COVID19, #mortality, #children, #SchoolClosures
Fast superhighway through the Solar System discovered - Big Think

bigthink.com/hard-science/f…

#ArchesOfChaos, #SpaceTravel, #SolarSystem, ScientificDiscovery
Read 20 tweets
Daily Bookmarks to GAVNet 12/08/2021 greeneracresvaluenetwork.wordpress.com/2021/12/08/dai…
As Bradford pears remain a nuisance in South Carolina, methods of attack range from bounties to bans

usatoday.com/story/news/nat…

#InvasiveSpecies #landscaping #BradfordPearTrees #EcosystemDamage #mitigation
Build Back Better’s Insulin Pricing Benefit Isn't Enough

newrepublic.com/article/164551…

#pharmaceuticals #insulin #PriceCaps #legislation #consequences
Read 13 tweets
🇬🇧Let's have a look at GRO deaths figures for #England & #Wales.
No bias, no manipulation, just a division into semesters.
Thanks to vaccination, excess #mortality was expected to disappear or at least collapse, but…🧐
Src: ons.gov.uk/peoplepopulati…
And yes, because there are spectacular peaks, forgetting the depressions that follow (harvest effect) and then the excesses that accumulate week after week and which hurt the population, silently…
What about other UK nations?
#Scotland #NorthIreland
The excess is quadrupled!
Src: @HMDatabase
@JamesMelville @scojw @jburnmurdoch
Read 6 tweets
Daily Bookmarks to GAVNet 11/18/2021 greeneracresvaluenetwork.wordpress.com/2021/11/18/dai…
Family spared trial over mummified remains of woman found on mattress

theguardian.com/uk-news/2021/n…

#MentalCondition #JusticeSystem #UnitedKingdom
Where will the next pandemic begin? The Amazon rainforest offers troubling clues

latimes.com/world-nation/s…

#pandemic #viruses #zoonosis #ClimateChange #deforestation #GlobalWarming
Read 8 tweets
The number of children infected with #Covid-19 is less among all other age group in the global population. How about the #psychological, #social impact in on #children? Researches suggests social and psychological impact in this group were mostly severe.
To find some answer and have idea let's take a closer look at the researches and figures provided by the United Nations Children's Fund (UNICEF), which shows the magnitude of the pandemic’s #impact on #children. Image
As families lose their sources of #income and home environments are turned upside down due to the socioeconomic impacts of Covid-19, #children find themselves more vulnerable to #poverty and likely to be deprived of their basic needs. Image
Read 26 tweets
I’m a Pediatrician = ❤️👶🏽🧑🏻👩🏾. I have worked in Children’s Hospitals, on medivac teams and now in the North. These are my thoughts on what we are facing with #Delta going into the fall
1. Wave 4 of #COVID will be a pandemic of #misinformation, under-vaccination and inadequate mitigating public health interventions (removing mask mandate, not addressing school ventilation, etc). We have reached the limits of what “encouraging people to get vaccinated” can do.
2. Who will pay the price? #Children, esp children < 12 who can’t be #VaxXed. It is misleading to say “not that many kids die”. #Mortality is a pretty crude outcome measure in #Pediatrics. What about disability, medical trauma, impact on families, mental health?
Read 8 tweets
"Er zijn nu in totaal 448 meldingen van overlijden na #COVID19 #Vaccinatie, maar daarvan ontbreekt vooralsnog een uitgebreide analyse." #Lareb
(Note: waarom weigert de overheid obductie, is er iets te verbergen in het experiment?🤔)
bnr.nl/nieuws/gezondh…
Alexov webinar transcript. Click on the link to read the translated interview of Dr. Stoyan Alexov, president of the #bulgarian Pathology Association. #COVID19
Int. Webinar May 8, 2020 #Corona p(l)andemic
off-guardian.org/alexov-webinar…
Italy #COVID19 hoax. “Stop lying! I have the true numbers!” (24 April 2020)
Vittorio Sgarbi, Chamber of Deputies of the Italian Parliament, warned that the majority of deaths were a part of a scheme to control the public with fear.
z3news.com/w/italy-hoax-l…
Read 4 tweets
What if you or your doctor could accurately predict how long you had to live upon a new diagnosis of aggressive cancer (e.g. lung cancer or sarcoma)? I've faced that question both as a doctor and with a dearly beloved. On the one hand I know I would 1/ #ML #AI #mortality
do the utmost to beat the odds forward.com/scribe/470514/… and a gloomy prediction would be just another hurdle to overcome. On the other hand, a very accurate predictor of mortality upon diagnosis would be very useful: we might dispense w control arms in trials [at our peril] 2/
families and society might allocate resources/support accordingly, research might focus on why exceptional patients deviate markedly from the prediction dbmi.hms.harvard.edu/news/most-powe… . Therefore a recent study by colleagues @HarvardDBMI @HarvardChanSPH @harvardmed on this prediction 3/
Read 8 tweets
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
» doi.org/10.1038/s41467…
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses. Image
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
» doi.org/10.1101/2021.0…
Japan Registry of Clinical Trials jRCTs071210011 Image
The influence of #HLA genotype on the severity of #COVID19 infection
» doi.org/10.1111/tan.14…
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic. Image
Read 199 tweets
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action. jjcouey.medium.com/5-concerns-abo…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
» doi.org/10.1126/scienc…
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus. Image
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
» doi.org/10.1007/s00415…
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component. Image
Read 213 tweets
March 2021, UN: "the disruption to #health services provision & access & the rising #food insecurity could lead to additional 253,500 – 1,157,000 #child #deaths & 12,200 – 56,700 #maternal deaths, globally."

#Lockdowns #SavingLives #SouthAsia #Genocide Image
"As a result of these disruptions in South Asia, #child #mortality could potentially increase by 18–40% & maternal mortality by 14–52%, over the next year."

1996, Albright: "We think the price is worth it."

2021, #Bourgeoisie, #together: "We think the price is worth it." Image
"Across #SouthAsia [], an estimated 89,434 additional #stillbirths are anticipated as a result of reduced coverage of essential *SRMNCH services.

...unsafe abortions are also expected to increase [] by more than 50%."

[*Sexual, Reproductive, Maternal, #Neonatal & Child Health] Image
Read 9 tweets
ICYMI, a reminder that this pandemic will have a lasting legacy beyond the tragedy of the countless lost lives and grieving families. Results from the #COVERSCAN study on #longcovid reports that organ impairment was detected in post COVID patients as shown in the figure below
This included damage to the #heart, #lungs, #kidneys, #liver, #pancreas and #spleen In almost a third of patients, damage in 2 or more organs was identified. In particular, damage to the liver, heart or lungs was associated with further organ impairment.
The participants in this study were all considered to be previously at low risk of #mortality and had no #comorbidities. bmjopen.bmj.com/content/11/3/e…
Read 6 tweets
I would say that society is at fault. The government was not behind Jenny McCarthy, Oprah, Dr. Oz, etc.
#vaccine #VaccinesSaveLives #VaccinesWork #MedTwitter #ScienceTwitter
What the government DID do wrong: “#security” & espionage via vaccines Frankenstein monster unleashed on Muslims

If the US government does do things like this it’s not a “#conspiracy

...all while what led to #CapitolRiots was brewing 🤦🏻‍♀️

@PeterHotez

npr.org/sections/thetw…
If Prius-driving Whole Foods-consuming suburbanites would STOP #misinformation #disinformation to #trauma ridden #refugee populations

(trauma->fear)

the jobs of minority & Muslim doctors would not be so hard

This is lack of *societal* control
of the most privileged
who HARM
Read 21 tweets
We live in an attention #economy & what #Tweetiatricians have known for decades (#Twitter started in 2006): importance of drawing attention to factual science-based information as compared to #misinformation & #disinformation, especially on #vaccines

econreview.berkeley.edu/paying-attenti…
You have to be fast & prolific to play catch up to this. I have 77K tweets, a moderate sized band of 6K followers interested enough to tolerate my volume but use of hashtags allows reach across Twittersphere. Trending hashtags = better for riding a way for that attention economy
If is unclear if we are now so siloed that tweets are ineffective with anti-vaxx. But not all anti-vaxx are QAnon
Read 39 tweets
This afternoon, I met with the three indigenes of Ekiti State who were recently honoured with the Presidential Award for @officialnyscng Corps members. I am glad that in their various Places of Primary Assignment (PPA) they demonstrated #leadership, #compassion, and #diligence...
- values that define us as Ekiti people.

These young people went beyond the call of duty and made us proud. Kolawole Toba Gabriel focused on maternal and child #mortality, and helped to address questions of #poverty that contribute to high mortality rates in Adamawa State.
In Bauchi State, Ayodele Olubusayo Abidemi did a lot to improve the learning environment in the community where she served by renovating three blocks of classrooms, and assisting #school children.
Read 7 tweets
This tweet thread is about the #Covid_19: Updates from Singapore webinar on 26 Feb 2021

I've been busy so this is ~ a month after

It will be followed by a tweet thread documenting a more recent episode that was last week
#Covid_19 : Updates from Singapore is a webinar organised by @WHOGOARN and @NUSMedicine

And moderated by @profdalefisher, Prof. David Allen, and Dr. Louisa Sun
We are joined tonight by Dr. Peter Karim Ben Embarek
Read 51 tweets
Der schwedische #Sonderweg von #Tegnell:
Eine #AITask-Analyse der Zusammenhänge
16.04.2020 - Der schwedische Staatsepidemiologe #Tegnell erklärte NRK.no seinen Plan, bis Mai 2020 in #Stockholm die #Herdenimmunität zu erreichen. Forscher aus #Schweden warnten Tegnell vor einer möglichen Katastrophe für die Bevölkerung nrk.no/urix/tegnell_-…
#Tegnell überzeugte die #Lövfen-Regierung, dass seine Strategie der #COVID-#Durchseuchung zur #Immunität führen könnte, und so die Bevölkerung vor einer möglichen zweiten Pandemie-Welle geschützt sein würde: Das #Experiment begann, mit #Stockholm npr.org/2020/04/26/845…
Read 27 tweets
#EU #Brussels #Coronavirus #Mortality #Statistic

Around March and December 2020, there were 580,000 more deaths in the EU than during the same time in 2016–2019. During the early stages of COVID-19's spread, excess mortality in the EU peaked in April 2020,
with a 25% increase over the average of the same month from 2016 to 2019. Between May and July, there was a decline in excess mortality, but with the second wave of the pandemic, a new increase in mortality began in August and September.
In August and September, excess mortality in the EU was 8% higher than the average, 18% higher in October, and 41% higher in November, followed by 30% higher in December.
Read 6 tweets
Finally got to analyze & put my thoughts together on the recent #posaconazole vs. #voriconazole phase 3 trial for invasive #aspergillosis published in .@TheLancet a few weeks ago.
Best is to put the major trials of the 3 #VIP triazoles done over the last 20 years in perspective!
Here is the table with key points of trial design of the #TresAmigos trials, interesting features:

#Vori-Ampho was open label, but with blinded adjudication, including to adverse effects.

All where non-inferiority trials, #vori-amphoB had a clause for claiming superiority.
Read 20 tweets
Reducing #COVID19 #Airborne #Transmission Risks on #PublicTransportation Buses
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%. Image
🔝#SARSCoV2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies. Image
High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others Image
Read 236 tweets

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