Discover and read the best of Twitter Threads about #mutagenesis
Most recents (3)
In silico identification of natural products from Centella asiatica as SARS-COV-2 main protease (M pro) inhibitor. 1/n
❌❌❌ #ritonavir #molnupiravir in #COVID19
No more #tryglyceride #mutagenesis
pubmed.ncbi.nlm.nih.gov/34345605/
❌❌❌ #ritonavir #molnupiravir in #COVID19
No more #tryglyceride #mutagenesis
pubmed.ncbi.nlm.nih.gov/34345605/
2/n 
Anti-Inflammatory and anti-vascular leakage effects by combination of Centella asiatica and Vitis vinifera L. (Grapevine) leaf extracts.
#antiinflammatory qualities #anti #vascular #leakage effect
hindawi.com/journals/ecam/…
#antiinflammatory qualities #anti #vascular #leakage effect
hindawi.com/journals/ecam/…
Ivermectin 0.2-0.4mg/kg works at the outer and inner part of cells, thru P2X, GlycineCls, has anti-inflammatory effects, proven for decades, etc.
Molnupiravir 800mg twice a day for 5 days, works thru the RdRp. Can this antiviral have the side effects similar to Remdesivir ?
Molnupiravir 800mg twice a day for 5 days, works thru the RdRp. Can this antiviral have the side effects similar to Remdesivir ?
Comparison studies about Molnupiravir.
Gordon et al. : the high frequencies of G-to-A and C-to-U transition mutations in coronaviruses exposed to molnupiravir.
#host DNA #mutagenesis possibility
nature.com/articles/s4159…
Gordon et al. : the high frequencies of G-to-A and C-to-U transition mutations in coronaviruses exposed to molnupiravir.
#host DNA #mutagenesis possibility
nature.com/articles/s4159…
Kabinger et al. entertains A-to-G transitions, which can occur in coronaviruses exposed to molnupiravir, albeit at much lower frequencies.
Thus, although the biochemical evidence indicates that molnupiravir triphosphate (MTP)
is a better CTP (natural nucleotide) analog, the ..
Thus, although the biochemical evidence indicates that molnupiravir triphosphate (MTP)
is a better CTP (natural nucleotide) analog, the ..
#PlantScienceClassics #2: Radiation-induced mutagenesis. 100 years ago, in 1921, Emmy Stein developed radiation-induced #mutagenesis of #Antirrhinum majus plants. But today it seems that her invaluable contribution is being ignored… Read on doi.org/10.1007/BF0195…
Mutagenesis is now an invaluable tool to understand a gene’s function. In the early 1900s, when the hereditary substance was not even identified yet, it was an even more important tool, which Emmy Stein added to the small toolbox available to biologists at the time.
Stein used gamma rays from radium to irradiate both, adult plants & seeds, & showed the effects of different doses & different lengths, determining the lethal dose, &, importantly, the dose that induced weak mutants, that would still produce seeds to continue experimental work.
