@SciImmunology

@SciImmunology

Most recents (3)

@Bergthalerlab

New insights into SARS-CoV-2 immune evasion

#SARS-CoV-2 #mutations can lead to antibody #escape. What about T cells? In our study in @SciImmunology we report how mutated epitopes evade T cell responses.
immunology.sciencemag.org/content/6/57/e… 1/7

@GISAID

Using deep viral sequencing we identified low-frequency mutations in experimentally validated CD8 T cell epitopes of SARS-CoV-2, some of which were found as fixed mutations in global virus sequences from @GISAID. 2/7

Guided by binding predictions we selected epitopes and #mutants for further biochemical investigations by cell-free MHC-I binding assays. These analyses suggested that single amino acid changes impair binding to MHC-I molecules. 3/7

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Occupy Schagen

@OccupySchagen

#Cassandra: #SARS1 bound "Spikes" to Human #ACE2 receptors ONLY. Those are rare in healthy people.

In #SARS2 & #MUTANTS (#COVID19) they now bind ALSO to #Furin receptors, as in #HIV/#AIDS & #Ebola, which makes it 1000 x as #Infectuous:

— RT World News rt.com/news/481837-co…

#Cassandra: January 2020 article:

Uncanny similarity of 4 unique #Inserts in the 2019-nCoV (SARS-CoV-2) spike protein to #HIV1 (AIDS) #Gp120 and #Gag:

->biorxiv.org/content/10.110…

@dimsum

#Cassandra: Article March 2020.

#SARS_CoV_2 (COVID19) is NOT Natural !

#Czech molecular biologist, Dr. Soňa Peková explains in layman terms that #COVID19 virus originates from a lab, and the Americans try to refute it (Updated):

dimsumdaily.hk/czech-molecula… via @dimsum Daily

Read 10 tweets

In_my_opinion

@Cb57860277