Discover and read the best of Twitter Threads about #myc

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What is the petrodollar and what it means for the changing world order.

Many know the importance of the US$ and how it confers a massive advantage to the US. This #thread explores the drivers of the petrodollar and how they will impact and shape the future as we know it. #myc
It is an open secret that the US and Saudi Arabia have a mutually beneficial relationship which stretches back decades.

This started in 1973, when Arab countries attacked Israel and sparked what is now known as the Yom Kippur war.
In an attempt to diffuse the situation, the US acted as an intermediary for diplomacy and supplied Israel with weapons and supplies.

In retaliation, OPEC countries triggered an oil price increase from $3/ barrel to as high as $17 and chose to reduce oil production by 25%.
Read 22 tweets
Delighted to share our new study nature.com/articles/s4158… introducing PhasED-Seq out today @NatureBiotech.
A fantastic collaboration from @StanfordMedicine led by Dave_Kurtz & Joanne Soo with @max_diehn to help transform #cancer interception & monitoring by improving #LiquidBiopsy #ctDNA detection of #MRD.
For many cancers & nearly all currently available techniques, the impressive KM plots of #ctDNA #MRD immediately after definitive Rx w/ curative-intent unfortunately still miss ~50% of all events which occur in the MRD-negative subset, thus having modest NPV.
Read 21 tweets
Our first paper authors.elsevier.com/a/1cRqD6tu0Cbo… is now out @CellStemCell! With @ionispharma & the Jamieson Lab @UCSanDiegoDRM, we found that selective #antisense oligonucleotides inhibiting #IRF4 reduce disease burden & #multiplemyeloma #regeneration in #cancer models. @CellPressNews 1/ Image
IRF4 (interferon regulatory factor 4) is a key plasma cell transcription factor that is known to play a critical role in #myeloma progression. It's been shown to activate networks of #cellcycle and cancer regulators, including the notorious #cancer and #stemcell gene, #MYC. 2/ Image
In this new work, the talented @PhoebeMondala & @AshniVora first dug deeper into the IRF4 networks activated in high-risk forms of #myeloma, including #plasmacellleukemia. IRF4 target genes (SLAMF7, BCMA) were widely induced, especially among genes regulating the #cellcycle. 3/ Image
Read 15 tweets

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