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So folks wanted a #journalclub on the @JAMAPediatrics paper on #epidurals and #autism. Ok......here we go!
1. Let's review the intro first. Beyond conjecture, they offer scant data to justify their study which was an animal study (ref 5). They say 'standard clinical doses of LAs 👇produce neurotoxic effects & altered neurobeh devlpment in monkeys.' 
These aren't standard doses. We use in fact substantially lower concentrations & doses of epidural local anesthetics. Plus, this small study in non-laboring monkeys included multiple behav outcomes. So high likelihood of chance finding. Also, anyone know if monkeys get ASD??
