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#NEPHTWEETORIAL #NEPHKIDS2020 LET'S TALK HYPOCALCEMIA!Ever wonder why we supplement 👶🏽 with Calcium while we're correcting Vitamin D deficiency/insufficiency?🤔More on that at the end of tweetorial! Let's deep-dive into physiology now!🏊🏽♂️🔽 @nikhil_Lohiya @jpsugumar @IPNA_PedNeph
99% of calcium is in 🦴. Of the tightly regulated serum calcium, 45% is albumin-bound 🤝, 55% is diffusible 💥(ionized Ca2, complex with HCO3 & Citrate). onlinelibrary.wiley.com/doi/abs/10.100…
Calcium homeostasis is intimately regulated by
🌜Parathyroid Hormone (PTH)
🌜Calcitonin
🌜Active Vitamin D
Whenever there's a drop⚠️⏬ in Calcium levels, 🦇 signal is sent out by Parathyroid glands to osteoclasts to release calcium from 🦴 via PTH.
🌜Parathyroid Hormone (PTH)
🌜Calcitonin
🌜Active Vitamin D
Whenever there's a drop⚠️⏬ in Calcium levels, 🦇 signal is sent out by Parathyroid glands to osteoclasts to release calcium from 🦴 via PTH.
#NEPHTWEETORIAL #NEPHKIDS2020 LET'S TALK DEHYDRATION!🥵 Welcome to our first tweetorial where we'll be discussing the pathophysiology of dehydration🤯& try and answer the WHAT, WHY, WHERE, WHEN, HOW in management.🤔 -@jpsugumar @IPNA_PedNeph
Our 👫🏽 body resembles the composition of Mother🌎. We're 2/3rd 💦 Let's look at this conceptual classification to understand which compartment of our 👫🏽 are affected the most according to underlying etiology. 
Similar to the droughts affecting our agricultural lands, DEHYDRATION affects our internal mileu resulting in physiological disturbances. 🌱🌾➡️🥀🍂
(from Askew EW. Water. In: Ziegler EE, Liler LJ, eds. Present Knowledge in Nutrition. 7th ed. Washington, DC: ILIS; 1996:98–108)
(from Askew EW. Water. In: Ziegler EE, Liler LJ, eds. Present Knowledge in Nutrition. 7th ed. Washington, DC: ILIS; 1996:98–108)
