Discover and read the best of Twitter Threads about #nephronophthisis
Most recents (1)
1/ đź’ĄHello, #Nephtwitter đź’Ą
⚡️Let’s talk a little bit about #ciliopathies today.
⚡️How are Nephronophthisis (NPHP), polycystic kidney disease (PKD), & in fact many cystic diseases (aka #ciliopathies) related?!
Join me in the exploration-
#tweetorial #MedTwitter #ASPNeph #NSMC
⚡️Let’s talk a little bit about #ciliopathies today.
⚡️How are Nephronophthisis (NPHP), polycystic kidney disease (PKD), & in fact many cystic diseases (aka #ciliopathies) related?!
Join me in the exploration-
#tweetorial #MedTwitter #ASPNeph #NSMC
2/ 💥Let’s begin with Cilia-
đź“ŚMotile cilia- generate flow of mucus & CSF
đź“ŚNon-motile/sensory cilia (inner ear, retina, & olfactory epithelium)
- plays a part in important pathways [Hedgehog, Wnt (wingless-Int-1), & PCP (planar cell polarity) signaling]
ncbi.nlm.nih.gov/pmc/articles/P…
đź“ŚMotile cilia- generate flow of mucus & CSF
đź“ŚNon-motile/sensory cilia (inner ear, retina, & olfactory epithelium)
- plays a part in important pathways [Hedgehog, Wnt (wingless-Int-1), & PCP (planar cell polarity) signaling]
ncbi.nlm.nih.gov/pmc/articles/P…
3/Now let’s move on to💥Cystoproteins💥
📌These are proteins in cilia when mutated → cystic kidney diseases in humans, mice, or zebrafish
đź“Śexpressed in primary cilia, basal bodies or centrosomes
📌These are proteins in cilia when mutated → cystic kidney diseases in humans, mice, or zebrafish
đź“Śexpressed in primary cilia, basal bodies or centrosomes
